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Protein Overview: HIS4_GEOSL

General Information:
Name(s) found: HIS4_GEOSL [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase OS=Geobacter sulfurreducens (strain ATCC 51573 / DSM 12127 / PCA) GN=hisA PE=3 SV=1 [Swiss-Prot]
    • Organism: Geobacter sulfurreducens PCA
    Length: 244 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: histidine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIVIPAIDLK EGKCVRLEQG LMEKDTVFCD NPADQAREWE RQGAELLHIV DLDGAFAGEP  60
   61 KNRASIEAIV KAIAIPTQLG GGIRDIPTIE AYLSLGIGRV ILGTAAQRNP ELVEEACRLF 120
  121 PGRIVVGIDA KNGMVAVQGW AEVTGVTAVD LAKRFEGYGV AAIIYTDIAR DGMMQGPNIE 180
  181 ATRALAEAIS IPVIASGGVS SLKDIENLMA IETSGIAGAI TGKAVYTGAI NLAEAVALTK 240
  241 RGGA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..244] PSI-BLAST 42.221849 Crystal structure of the bifunctional protein Pria

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • imidazoleglycerol-phosphate synthase activity
    		•  8.63799159510181 bayes_pls_golite062009
  • catalytic activity
    		•  2.44231061702877 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  1.13340776845419 bayes_pls_golite062009
  • indole-3-glycerol-phosphate synthase activity
    		•  0.549444136526559 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  0.426391242491024 bayes_pls_golite062009
  • lyase activity
    		•  0.258652421339738 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle