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Protein Overview: SYA_SHEON

General Information:
Name(s) found: SYA_SHEON [Swiss-Prot]
Description(s) found:
Found 5 descriptions.
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  • Alanine--tRNA ligase OS=Shewanella oneidensis (strain MR-1) GN=alaS PE=3 SV=1 [Swiss-Prot]
    • Organism: Shewanella oneidensis MR-1
    Length: 874 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: alanyl-tRNA aminoacylation [ISSLink to PubMed article]
    Molecular Function: alanine-tRNA ligase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MYQTTAALRS AFLEFFRSNG HQVVDSSSLV PGNDPTLLFT NAGMNQFKDV FLGMDKRSYT  60
   61 RATTAQRCVR AGGKHNDLDN VGYTARHHTF FEMLGNFSFG DYFKEDAIRF GWTFLTEVLM 120
  121 LPKERLCVTI YQTDDEAFEI WNKKIGVAAE NIIRIGDNKG APYASDNFWQ MGDTGPCGPC 180
  181 TEIFYDHGDH IWGGRPGSPE EDGDRFIEIW NIVFMQYNRQ ASGEMLPLPK PSVDTGMGIE 240
  241 RIAAIMQGVH SNYEIDIFRA LIAKAAEIIG VADLSNKSLR VIADHIRSCA FLVADGVMPS 300
  301 NEGRGYVLRR IIRRAVRHGN KLGATEAFFY KLVPTLIDVM GDAAKGLAET QVIVEKALKA 360
  361 EEEQFARTLE RGLGILDSAL NELQGDTLDG ETVFKLYDTY GFPVDLTADV CRERNIIVDE 420
  421 AGFEAAMAEQ RSRAQAAGNF GADYNAALKI DAETAFCGYS ELTGNAKVTA LYLNGESVPA 480
  481 INTGDDAVVV LDVTPFYAES GGQVGDKGVL MAQGIEFTVN DTQKFGQASG HKGTLTAGSL 540
  541 SVGQVLEAKV DKKLRHRTQL NHSVTHLLHA ALRQVLGTHV TQKGSLVDPE RLRFDFSHFE 600
  601 AVKPFELKQV EELVNTQIRR NHELKVAEMA IDEAKEKGAM ALFGEKYDSQ VRVVTMGDFS 660
  661 IELCGGTHVG RTGDIGLFKI TSEGGIAAGV RRIEAVTGAA AMAYVAQQQA ELEEAASLLK 720
  721 ADAHSVVTKL KVQLDKMKQL EKEMQQLKDK LAAAASADLA GDAVVVNGVN VLIKKLEGVE 780
  781 AGALRGLQDE LKQKLKSAII VLGVAQEGKV NLIAGVSNDL IAKIKAGELV AMVATQVGGK 840
  841 GGGRPDMAQA GGSQPENLDA ALSQVLPWIT ERLA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..463] PSI-BLAST 1000.0 The crystal structure of the catalytic fragment of the alanyl-tRNA synthetase
    2 View Details [464..745] PSI-BLAST 55.09691 Structure of Staphylococcus aureus threonyl-tRNA synthetase complexed with an analogue of threonyl adenylate
    3 View Details [746..874] Pfam 18.853872 No description for PF02272.10 was found. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  7.89468709683036 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  7.89468709683036 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  7.88410036819636 bayes_pls_golite062009
  • ligase activity
    		•  6.92073480193262 bayes_pls_golite062009
  • alanine-tRNA ligase activity
    		•  6.00693881794242 bayes_pls_golite062009
  • phenylalanine-tRNA ligase activity
    		•  2.76416144738864 bayes_pls_golite062009
  • threonine-tRNA ligase activity
    		•  2.18642354927 bayes_pls_golite062009
  • glycine-tRNA ligase activity
    		•  2.17047432052132 bayes_pls_golite062009
  • serine-tRNA ligase activity
    		•  2.07594942154162 bayes_pls_golite062009
  • catalytic activity
    		•  1.99372273395202 bayes_pls_golite062009
  • lysine-tRNA ligase activity
    		•  1.72324031407565 bayes_pls_golite062009
  • histidine-tRNA ligase activity
    		•  1.72215103383322 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.03781135697387 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.0144617399226 bayes_pls_golite062009
  • asparagine-tRNA ligase activity
    		•  0.921492123574877 bayes_pls_golite062009
  • binding
    		•  0.904147650999471 bayes_pls_golite062009
  • DNA binding
    		•  0.8162402823536 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.433976751263 bayes_pls_golite062009
  • transcription factor activity
    		•  0.140257788851398 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.00572514744734753 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle