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Protein Overview: gi|24374925, gi|...

General Information:
Name(s) found: gi|24374925 [NCBI NR]
gi|24349634 [NCBI NR]
Description(s) found:
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  • gi|24374925|ref|NP_718968.1| bifunctional aspartokinase I/homeserine dehydrogenase I [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24349634|gb|AAN56412.1|AE015777_7 aspartokinase I/homoserine dehydrogenase, threonine-sensitive [Shewanella oneidensis MR-1] [NCBI NR]
  • aspartokinase I/homoserine dehydrogenase, threonine-sensitive [Shewanella oneidensis MR-1]gi|24349634|gb|AAN56412.1| aspartokinase I/homoserine dehydrogenase, threonine-sensitive [Shewanella oneidensis MR-1] [nrdb_11152004_Chlamydomonas]
  • aspartokinase I/homoserine dehydrogenase, threonine-sensitive [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
  • bifunctional aspartokinase I/homeserine dehydrogenase I [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 822 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: methionine biosynthetic process [ISSLink to PubMed article]
    lysine biosynthetic process via diaminopimelate [ISSLink to PubMed article]
    threonine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: aspartate kinase activity [ISSLink to PubMed article]
    homoserine dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVMKFGGTS LANWQRFSMA ADIVAKAATM EPVATVLSAP ATVTNALLEM VNLAVKGEDY  60
   61 SPVIQHVERV FTSLYQDAVS SGLSSTQSEL LFAGLGAQLA RWQDRLHGIT LLQECPDGIC 120
  121 AEIVVAGERL SAALMEQVML AKGITSAQLD PRKLFLGRGR PLESVVDIAV SKPRFKNLLL 180
  181 DEKRVWVMPG FTAADEDGKV VTLGRNGSDY SAAVLAACLD ASSCEIWTDV DGVYNTDPRV 240
  241 VADAKLLSQL SYQEAMELSY FGAKVLHPKT IAPIAQFHIP CYIKNSFNPD APGTLVSNLA 300
  301 DASGLQVKAI SNLDNQTMFD VSGPGMKGMV GMASRTLAAI SRSGVSVSLI TQSSCEYSIS 360
  361 FCVATSESAK VKLALEQEFE LEIKSDLLEP IEMRHDLAIV SLIGDGMRTH KGVAARFFQA 420
  421 LAQASVNIIA IAQGSSERSI STVIEQRKTK HAVAACHQGF FDVQQYLDVF LVGCGNVGAG 480
  481 LLEQIKQQAI VLKEQHISIR VCGIVNSSKM LLDSAGIDLN NWQNLLADSQ QSSDLPALLA 540
  541 WVKEQQLLNP VLVDCTSSEQ VSNQYLEVMN AGMHVVTPNK KANTRDYAYY QALRQTALTQ 600
  601 RRQFLYETNV GAGLPVIDNL KKLLFAGDKL HKFNGILSGS LSFIFGKLDE GMSLSEATKL 660
  661 AREKCFTEPD PRDDLSGMDV ARKVLILARE VGLKLELSDI VVDSVLPESF DDSGDVESFM 720
  721 ARLPEADAAI AARVAEAKAQ GKVLRYVGQI EEGACHVRIA EVDATDPLYS VKGGENALAF 780
  781 YSRYYQPIPF VLRGYGAGTE VTAAGAFADV LRTLNWTREV SV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..462] PSI-BLAST 101.0 No description for 2hmfA was found.
    2 View Details [463..822] PSI-BLAST 66.39794 Homoserine dehydrogenase

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • kinase activity
    		•  3.6039877609535 bayes_pls_golite062009
  • acetolactate synthase activity
    		•  3.48670706716817 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.26420758063619 bayes_pls_golite062009
  • aspartate kinase activity
    		•  3.23731032633773 bayes_pls_golite062009
  • transferase activity
    		•  3.047646907595 bayes_pls_golite062009
  • catalytic activity
    		•  2.83338756483354 bayes_pls_golite062009
  • phosphotransferase activity, carboxyl group as acceptor
    		•  2.65970393362911 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.54193538468834 bayes_pls_golite062009
  • amino acid kinase activity
    		•  2.38310367076654 bayes_pls_golite062009
  • transferase activity, transferring aldehyde or ketonic groups
    		•  2.27460110663386 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.77420728550693 bayes_pls_golite062009
  • DNA binding
    		•  1.70654139251388 bayes_pls_golite062009
  • binding
    		•  1.61057316956254 bayes_pls_golite062009
  • acetylglutamate kinase activity
    		•  1.28891782911186 bayes_pls_golite062009
  • transcription factor activity
    		•  1.13755026342338 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.61058430787131 bayes_pls_golite062009
  • glutamate 5-kinase activity
    		•  0.416864856459166 bayes_pls_golite062009
  • protein binding
    		•  0.178881469836152 bayes_pls_golite062009
    2
    Term Confidence Notes
  • catalytic activity
    		•  2.54843319568228 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.90939908578582 bayes_pls_golite062009
  • oxidoreductase activity
    		•  1.84451425136793 bayes_pls_golite062009
  • DNA binding
    		•  1.61355789916908 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.48478425318425 bayes_pls_golite062009
  • binding
    		•  1.22114607236074 bayes_pls_golite062009
  • transcription factor activity
    		•  0.91090893050278 bayes_pls_golite062009
  • phosphoglycerate dehydrogenase activity
    		•  0.639509916626856 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  0.610531769148819 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor
    		•  0.610013758225609 bayes_pls_golite062009
  • saccharopine dehydrogenase activity
    		•  0.495113665163626 bayes_pls_golite062009
  • structural molecule activity
    		•  0.345975336806588 bayes_pls_golite062009
  • N-acetyl-gamma-glutamyl-phosphate reductase activity
    		•  0.0651785123513661 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle