Protein Overview: gi|24374925, gi|...

General Information:
Name(s) found:	gi\|24374925 [NCBI NR] gi\|24349634 [NCBI NR]
Description(s) found: Found 5 descriptions. SHOW ALL	gi\|24374925\|ref\|NP_718968.1\| bifunctional aspartokinase I/homeserine dehydrogenase I [Shewanella oneidensis MR-1] [NCBI NR] gi\|24349634\|gb\|AAN56412.1\|AE015777_7 aspartokinase I/homoserine dehydrogenase, threonine-sensitive [Shewanella oneidensis MR-1] [NCBI NR]
Organism:	Shewanella oneidensis MR-1
Length:	822 amino acids
Gene Ontology:
Cellular Component:	NONE FOUND
Biological Process:	methionine biosynthetic process [ISS] lysine biosynthetic process via diaminopimelate [ISS] threonine biosynthetic process [ISS]
Molecular Function:	aspartate kinase activity [ISS] homoserine dehydrogenase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKVMKFGGTS LANWQRFSMA ADIVAKAATM EPVATVLSAP ATVTNALLEM VNLAVKGEDY  60
   61 SPVIQHVERV FTSLYQDAVS SGLSSTQSEL LFAGLGAQLA RWQDRLHGIT LLQECPDGIC 120
  121 AEIVVAGERL SAALMEQVML AKGITSAQLD PRKLFLGRGR PLESVVDIAV SKPRFKNLLL 180
  181 DEKRVWVMPG FTAADEDGKV VTLGRNGSDY SAAVLAACLD ASSCEIWTDV DGVYNTDPRV 240
  241 VADAKLLSQL SYQEAMELSY FGAKVLHPKT IAPIAQFHIP CYIKNSFNPD APGTLVSNLA 300
  301 DASGLQVKAI SNLDNQTMFD VSGPGMKGMV GMASRTLAAI SRSGVSVSLI TQSSCEYSIS 360
  361 FCVATSESAK VKLALEQEFE LEIKSDLLEP IEMRHDLAIV SLIGDGMRTH KGVAARFFQA 420
  421 LAQASVNIIA IAQGSSERSI STVIEQRKTK HAVAACHQGF FDVQQYLDVF LVGCGNVGAG 480
  481 LLEQIKQQAI VLKEQHISIR VCGIVNSSKM LLDSAGIDLN NWQNLLADSQ QSSDLPALLA 540
  541 WVKEQQLLNP VLVDCTSSEQ VSNQYLEVMN AGMHVVTPNK KANTRDYAYY QALRQTALTQ 600
  601 RRQFLYETNV GAGLPVIDNL KKLLFAGDKL HKFNGILSGS LSFIFGKLDE GMSLSEATKL 660
  661 AREKCFTEPD PRDDLSGMDV ARKVLILARE VGLKLELSDI VVDSVLPESF DDSGDVESFM 720
  721 ARLPEADAAI AARVAEAKAQ GKVLRYVGQI EEGACHVRIA EVDATDPLYS VKGGENALAF 780
  781 YSRYYQPIPF VLRGYGAGTE VTAAGAFADV LRTLNWTREV SV

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..462]	PSI-BLAST	101.0	No description for 2hmfA was found.
2	View Details	[463..822]	PSI-BLAST	66.39794	Homoserine dehydrogenase

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
kinase activity	3.6039877609535	bayes_pls_golite062009
acetolactate synthase activity	3.48670706716817	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	3.26420758063619	bayes_pls_golite062009
aspartate kinase activity	3.23731032633773	bayes_pls_golite062009
transferase activity	3.047646907595	bayes_pls_golite062009
catalytic activity	2.83338756483354	bayes_pls_golite062009
phosphotransferase activity, carboxyl group as acceptor	2.65970393362911	bayes_pls_golite062009
transcription regulator activity	2.54193538468834	bayes_pls_golite062009
amino acid kinase activity	2.38310367076654	bayes_pls_golite062009
transferase activity, transferring aldehyde or ketonic groups	2.27460110663386	bayes_pls_golite062009
nucleic acid binding	1.77420728550693	bayes_pls_golite062009
DNA binding	1.70654139251388	bayes_pls_golite062009
binding	1.61057316956254	bayes_pls_golite062009
acetylglutamate kinase activity	1.28891782911186	bayes_pls_golite062009
transcription factor activity	1.13755026342338	bayes_pls_golite062009
transcription repressor activity	0.61058430787131	bayes_pls_golite062009
glutamate 5-kinase activity	0.416864856459166	bayes_pls_golite062009
protein binding	0.178881469836152	bayes_pls_golite062009

2

Term	Confidence	Notes
catalytic activity	2.54843319568228	bayes_pls_golite062009
transcription regulator activity	1.90939908578582	bayes_pls_golite062009
oxidoreductase activity	1.84451425136793	bayes_pls_golite062009
DNA binding	1.61355789916908	bayes_pls_golite062009
nucleic acid binding	1.48478425318425	bayes_pls_golite062009
binding	1.22114607236074	bayes_pls_golite062009
transcription factor activity	0.91090893050278	bayes_pls_golite062009
phosphoglycerate dehydrogenase activity	0.639509916626856	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	0.610531769148819	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor	0.610013758225609	bayes_pls_golite062009
saccharopine dehydrogenase activity	0.495113665163626	bayes_pls_golite062009
structural molecule activity	0.345975336806588	bayes_pls_golite062009
N-acetyl-gamma-glutamyl-phosphate reductase activity	0.0651785123513661	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.60

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle