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Protein Overview: HIS4_SHEON

General Information:
Name(s) found: HIS4_SHEON [Swiss-Prot]
Description(s) found:
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  • gi|24373629|ref|NP_717672.1| 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24347967|gb|AAN55116.1|AE015648_9 phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Shewanella oneidensis MR-1] [NCBI NR]
  • 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase OS=Shewanella oneidensis (strain MR-1) GN=hisA PE=3 SV=1 [Swiss-Prot]
  • phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Shewanella oneidensis MR-1]gi|24347967|gb|AAN55116.1| phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Shewanella oneidensis MR-1]gi|31563136|sp|Q8EFB5|HIS4 [nrdb_11152004_Chlamydomonas]
  • 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
  • phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 245 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: histidine biosynthetic process [ISSLink to PubMed article]
    Molecular Function: 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIPAIDLID GKVVRLYQGD YGQQTTFDLS PLAQLQSYQA QDASWLHIVD LTGAKDPAKR  60
   61 QTALIAALTA GLSANIQVGG GIRTEEQVAE LLSLGVKRVV IGSLAVKEPE LVKGWFNKFG 120
  121 NEAICLALDI NITPSGEKIV AVSGWQNGGG KNLESIVEDF SQVGLKHALV TDISRDGTLT 180
  181 GANTELYCEL SSRYPNIAWQ ASGGIASLED VAAVRDSGAA GIIIGKALLI NQFNVAEAIQ 240
  241 CWPNE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..245] PSI-BLAST 29.69897 Crystal structure of the bifunctional protein Pria

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • imidazoleglycerol-phosphate synthase activity
    		•  8.63799159510181 bayes_pls_golite062009
  • catalytic activity
    		•  2.44231061702877 bayes_pls_golite062009
  • transferase activity, transferring pentosyl groups
    		•  1.13340776845419 bayes_pls_golite062009
  • indole-3-glycerol-phosphate synthase activity
    		•  0.549444136526559 bayes_pls_golite062009
  • tryptophan synthase activity
    		•  0.426391242491024 bayes_pls_golite062009
  • lyase activity
    		•  0.258652421339738 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.91

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle