YRC Public Data Repository - Protein Structure Prediction

Protein:	HIS4_SHEON
Organism:	Shewanella oneidensis MR-1
Length:	245 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HIS4_SHEON.

Description	E-value	Query Range	Subject Range
HIS6_METFK - Imidazole glycerol phosphate synthase subunit HisF OS=Methylobacillus flagellatus (strain KT / ATCC ...	186.0	[0..2]	[245..7]
HIS6_DESHD - Imidazole glycerol phosphate synthase subunit HisF OS=Desulfitobacterium hafniense (strain DCB-2 / D...	185.0	[0..2]	[244..6]
HIS6_DESHY - Imidazole glycerol phosphate synthase subunit HisF OS=Desulfitobacterium hafniense (strain Y51) GN=h...	185.0	[0..2]	[244..7]
HIS6_PELTS - Imidazole glycerol phosphate synthase subunit HisF OS=Pelotomaculum thermopropionicum (strain DSM 13...	184.0	[0..2]	[244..6]
HIS6_GEOSL - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacter sulfurreducens (strain ATCC 51573 / ... HIS6_GEOSL - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacter sulfurreducens GN=hisF PE=3 SV=1	184.0	[0..2]	[244..6]
HIS6_CUPMC - Imidazole glycerol phosphate synthase subunit HisF OS=Cupriavidus metallidurans (strain ATCC 43123 /...	183.0	[0..2]	[245..6]
gi\|89098778, gi\|... - gi\|89098778\|ref\|ZP_01171659.1\| imidazole glycerol phosphate synthase subunit HisF [Bacillus sp. NRRL...	183.0	[0..2]	[245..6]
HIS6_GEOKA - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacillus kaustophilus GN=hisF PE=3 SV=1 HIS6_GEOKA - Imidazole glycerol phosphate synthase subunit HisF OS=Geobacillus kaustophilus (strain HTA426) GN=hi...	182.0	[0..2]	[245..6]
HIS6_ALCBS - Imidazole glycerol phosphate synthase subunit HisF OS=Alcanivorax borkumensis (strain ATCC 700651 / ...	182.0	[0..2]	[244..7]
gi\|89083520, gi\|... - gi\|89092432\|ref\|ZP_01165386.1\| imidazole glycerol phosphate synthase subunit HisF [Oceanospirillum s...	182.0	[0..2]	[245..7]

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Predicted Domain #1

Region A:
Residues: [1-245]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MIIPAIDLID GKVVRLYQGD YGQQTTFDLS PLAQLQSYQA QDASWLHIVD LTGAKDPAKR  60
   61 QTALIAALTA GLSANIQVGG GIRTEEQVAE LLSLGVKRVV IGSLAVKEPE LVKGWFNKFG 120
  121 NEAICLALDI NITPSGEKIV AVSGWQNGGG KNLESIVEDF SQVGLKHALV TDISRDGTLT 180
  181 GANTELYCEL SSRYPNIAWQ ASGGIASLED VAAVRDSGAA GIIIGKALLI NQFNVAEAIQ 240
  241 CWPNE

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	29.69897
Match:	1vzwA
Description:	Crystal structure of the bifunctional protein Pria
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
imidazoleglycerol-phosphate synthase activity	8.63799159510181	bayes_pls_golite062009
catalytic activity	2.44231061702877	bayes_pls_golite062009
transferase activity, transferring pentosyl groups	1.13340776845419	bayes_pls_golite062009
indole-3-glycerol-phosphate synthase activity	0.549444136526559	bayes_pls_golite062009
tryptophan synthase activity	0.426391242491024	bayes_pls_golite062009
lyase activity	0.258652421339738	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: