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Protein Overview: gi|24346978, gi|...

General Information:
Name(s) found: gi|24372866 [NCBI NR]
gi|24346978 [NCBI NR]
Description(s) found:
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  • gi|24372866|ref|NP_716908.1| DNA primase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24346978|gb|AAN54353.1|AE015572_8 DNA primase [Shewanella oneidensis MR-1] [NCBI NR]
  • DNA primase [Shewanella oneidensis MR-1]gi|24346978|gb|AAN54353.1| DNA primase [Shewanella oneidensis MR-1] [nrdb_11152004_Chlamydomonas]
  • DNA primase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 574 amino acids

    Gene Ontology:
    Cellular Component: alpha DNA polymerase:primase complex [ISSLink to PubMed article]
    Biological Process: DNA replication, synthesis of RNA primer [ISSLink to PubMed article]
    Molecular Function: DNA primase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIPRDFINE LIARTDIVEL IDRKVPLKKA GKNYSACCPF HSEKSPSFTV SRDKQFYHCF  60
   61 GCGAHGNAID FVMEYDRLDF VDAIEDLAGQ LGLEVPREQG TGKRQDDGLS RDLYQLMEEA 120
  121 SRFFQTQLRQ HQDKQKVIDY LAYRGLSDDI VEHFGIGFAP DGWDGLLSRY RQNQDAQDKL 180
  181 LTAGMLISND SGKRYDRFRD RLMFPIRDRR GRVIGFGGRV LGDGTPKYLN SPETPIFHKG 240
  241 NELYGLYELK QRHRDPDKVL IVEGYMDVVA LAQYGVDYAV ASLGTSTTAE QFQLLLRSAK 300
  301 EVICCYDGDR AGNEAAWRAL ETALPLLKPG DKVRFMFLPQ SEDPDSMVRK IGKDPFEQLM 360
  361 ESAITLPEFL FDTLATKFGT DKGNLAKQAF GLIEKIQDTV LQNLLLENLA HKLGMNSSDD 420
  421 MKKKLGFTVK QPKPTASTGL KGRGTPLRLA IALLVQHPEL GVGLSPQPAL NHLQMPGIDL 480
  481 LPLLLALTRE HRLNSAQLLE QFRDSPHSGT LHKLAQWDHQ VAEENQLEKF KQTLVWLNNQ 540
  541 YIEQRYQELS LKQTHTKEEK IQLQKLISVM KGLN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..97] PSI-BLAST 36.39794 Zinc-binding domain of DNA primase
    2 View Details [98..158] PSI-BLAST 93.522879 DNA primase DnaG catalytic core
    3 View Details [159..574] PSI-BLAST 31.30103 The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • DNA primase activity
    		•  9.73419395042405 bayes_pls_golite062009
  • transcription regulator activity
    		•  3.46382129825313 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  3.39768224850127 bayes_pls_golite062009
  • RNA polymerase activity
    		•  3.39768224850127 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  3.28799371541043 bayes_pls_golite062009
  • binding
    		•  2.62275087285714 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.95935440221316 bayes_pls_golite062009
  • DNA binding
    		•  1.92092218509957 bayes_pls_golite062009
  • transcription elongation regulator activity
    		•  1.49626290953998 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  1.23314259311645 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  0.730134088263314 bayes_pls_golite062009
  • catalytic activity
    		•  0.434839928397784 bayes_pls_golite062009
  • protein binding
    		•  0.265222284938592 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.240481799431949 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • DNA primase activity
    		•  11.9648478190162 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  4.35308216592295 bayes_pls_golite062009
  • RNA polymerase activity
    		•  4.35308216592295 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  4.2392655850006 bayes_pls_golite062009
  • binding
    		•  2.46518385502315 bayes_pls_golite062009
  • catalytic activity
    		•  1.39967796334655 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  1.17252562283519 bayes_pls_golite062009
  • transferase activity
    		•  0.605239890876961 bayes_pls_golite062009
  • protein binding
    		•  0.11913220264667 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle