Protein Overview: gi|24346978, gi|...

General Information:
Name(s) found:	gi\|24372866 [NCBI NR] gi\|24346978 [NCBI NR]
Description(s) found: Found 4 descriptions. SHOW ALL	gi\|24372866\|ref\|NP_716908.1\| DNA primase [Shewanella oneidensis MR-1] [NCBI NR] gi\|24346978\|gb\|AAN54353.1\|AE015572_8 DNA primase [Shewanella oneidensis MR-1] [NCBI NR]
Organism:	Shewanella oneidensis MR-1
Length:	574 amino acids
Gene Ontology:
Cellular Component:	alpha DNA polymerase:primase complex [ISS]
Biological Process:	DNA replication, synthesis of RNA primer [ISS]
Molecular Function:	DNA primase activity [ISS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAIPRDFINE LIARTDIVEL IDRKVPLKKA GKNYSACCPF HSEKSPSFTV SRDKQFYHCF  60
   61 GCGAHGNAID FVMEYDRLDF VDAIEDLAGQ LGLEVPREQG TGKRQDDGLS RDLYQLMEEA 120
  121 SRFFQTQLRQ HQDKQKVIDY LAYRGLSDDI VEHFGIGFAP DGWDGLLSRY RQNQDAQDKL 180
  181 LTAGMLISND SGKRYDRFRD RLMFPIRDRR GRVIGFGGRV LGDGTPKYLN SPETPIFHKG 240
  241 NELYGLYELK QRHRDPDKVL IVEGYMDVVA LAQYGVDYAV ASLGTSTTAE QFQLLLRSAK 300
  301 EVICCYDGDR AGNEAAWRAL ETALPLLKPG DKVRFMFLPQ SEDPDSMVRK IGKDPFEQLM 360
  361 ESAITLPEFL FDTLATKFGT DKGNLAKQAF GLIEKIQDTV LQNLLLENLA HKLGMNSSDD 420
  421 MKKKLGFTVK QPKPTASTGL KGRGTPLRLA IALLVQHPEL GVGLSPQPAL NHLQMPGIDL 480
  481 LPLLLALTRE HRLNSAQLLE QFRDSPHSGT LHKLAQWDHQ VAEENQLEKF KQTLVWLNNQ 540
  541 YIEQRYQELS LKQTHTKEEK IQLQKLISVM KGLN

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data

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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#		Region(s)	Method	Confidence	Match Description
1	View Details	[1..97]	PSI-BLAST	36.39794	Zinc-binding domain of DNA primase
2	View Details	[98..158]	PSI-BLAST	93.522879	DNA primase DnaG catalytic core
3	View Details	[159..574]	PSI-BLAST	31.30103	The Crystal Structure of the Bifunctional Primase-Helicase of Bacteriophage T7

Functions predicted (by domain):

#

Gene Ontology predictions

1

Term	Confidence	Notes
DNA primase activity	9.73419395042405	bayes_pls_golite062009
transcription regulator activity	3.46382129825313	bayes_pls_golite062009
DNA-directed RNA polymerase activity	3.39768224850127	bayes_pls_golite062009
RNA polymerase activity	3.39768224850127	bayes_pls_golite062009
nucleotidyltransferase activity	3.28799371541043	bayes_pls_golite062009
binding	2.62275087285714	bayes_pls_golite062009
nucleic acid binding	1.95935440221316	bayes_pls_golite062009
DNA binding	1.92092218509957	bayes_pls_golite062009
transcription elongation regulator activity	1.49626290953998	bayes_pls_golite062009
general RNA polymerase II transcription factor activity	1.23314259311645	bayes_pls_golite062009
RNA polymerase II transcription factor activity	0.730134088263314	bayes_pls_golite062009
catalytic activity	0.434839928397784	bayes_pls_golite062009
protein binding	0.265222284938592	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	0.240481799431949	bayes_pls_golite062009

2

No functions predicted.

3

Term	Confidence	Notes
DNA primase activity	11.9648478190162	bayes_pls_golite062009
DNA-directed RNA polymerase activity	4.35308216592295	bayes_pls_golite062009
RNA polymerase activity	4.35308216592295	bayes_pls_golite062009
nucleotidyltransferase activity	4.2392655850006	bayes_pls_golite062009
binding	2.46518385502315	bayes_pls_golite062009
catalytic activity	1.39967796334655	bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups	1.17252562283519	bayes_pls_golite062009
transferase activity	0.605239890876961	bayes_pls_golite062009
protein binding	0.11913220264667	bayes_pls_golite062009

Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

Philius Transmembrane Prediction:

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Source: Reynolds et al. (2008)

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle