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Protein Overview: TPMT_SHEON

General Information:
Name(s) found: TPMT_SHEON [Swiss-Prot]
Description(s) found:
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  • gi|24372175|ref|NP_716217.1| thiopurine S-methyltransferase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24346078|gb|AAN53662.1|AE015505_5 thiopurine S-methyltransferase [Shewanella oneidensis MR-1] [NCBI NR]
  • Thiopurine S-methyltransferase OS=Shewanella oneidensis (strain MR-1) GN=tpm PE=3 SV=1 [Swiss-Prot]
  • thiopurine S-methyltransferase [Shewanella oneidensis MR-1]gi|24346078|gb|AAN53662.1| thiopurine S-methyltransferase [Shewanella oneidensis MR-1] [nrdb_11152004_Chlamydomonas]
  • thiopurine S-methyltransferase [Shewanella oneidensis MR-1] [nr-271106-contam.fasta]
    • Organism: Shewanella oneidensis MR-1
    Length: 218 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: response to metal ion [ISSLink to PubMed article]
    Molecular Function: thiopurine S-methyltransferase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEPGFWHEKW QQQQIGFHQQ DVNPFLVTYW HQLALPADAK IFVPLCGKSL DMCFLAEQGH  60
   61 QVIGCELNEL AVQQFFSDNQ LPMQQSAEGE HQHYQTEQIS LYQGDIFTLP QSITAEVSGF 120
  121 YDRAALIAWP ESMRAQYAKQ LAYLLPQGSV GLLVTLDYPQ EVLSGPPFAV SPTWVETHLS 180
  181 EDFEIQPLAC QDVLADNPRF VKKAVPWLNE AVYLLKRR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..218] PSI-BLAST 26.09691 Solution structure of thiopurine methyltransferase from Pseudomonas syringae

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • thiopurine S-methyltransferase activity
    		•  2.46265304635007 bayes_pls_golite062009
  • transferase activity
    		•  1.77671966857605 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • methyltransferase activity
    		•  1.06467956103007 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  1.04881630872808 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  0.663101162414044 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle