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Protein Overview: gi|24372021, gi|...

General Information:
Name(s) found: gi|24372021 [NCBI NR]
gi|24345885 [NCBI NR]
Description(s) found:
Found 5 descriptions.
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  • gi|24372021|ref|NP_716063.1| dihydrolipoamide dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR]
  • gi|24345885|gb|AAN53508.1|AE015490_9 pyruvate dehydrogenase complex, E3 component, lipoamide dehydrogenase [Shewanella oneidensis MR-1] [NCBI NR]
    • Organism: Shewanella oneidensis MR-1
    Length: 475 amino acids

    Gene Ontology:
    Cellular Component: cytosolic pyruvate dehydrogenase complex [ISSLink to PubMed article]
    Biological Process: acetyl-CoA biosynthetic process from pyruvate [ISSLink to PubMed article]
    Molecular Function: pyruvate dehydrogenase activity [ISSLink to PubMed article]
    dihydrolipoyl dehydrogenase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNEIKTQVV VLGAGPAGYS AAFRAADLGL ETVIVERFST LGGVCLNVGC IPSKALLHVA  60
   61 KVIEEAKAVA AHGVVFGEPT IDLDKLRSFK QKVISQLTGG LGGMSKMRKV NVVNGFGKFS 120
  121 GPNSLEVTAE DGTVTVVKFD QAIIAAGSRP IKLPFIPHED PRIWDSTDAL ELKEVPGKLL 180
  181 VMGGGIIGLE MGTVYSSLGS EIDVVEMFDQ VIPAADKDVV RVFTKQIKKK FNLILETKVT 240
  241 AVEAREDGIY VSMEGKSAPA EPVRYDAVLV AIGRTPNGKL IDAEKAGVKI DERGFINVDK 300
  301 QLRTNVPHIY AIGDIVGQPM LAHKGVHEGH VAAEVIAGMK HYFDPKVIPS IAYTDPEVAW 360
  361 VGLTEKEAKE QGIAYETATF PWAASGRAIA SDCSEGMTKL IFDKDTHRVI GGAIVGVNGG 420
  421 ELLGEIGLAI EMGCDAEDLA LTIHAHPTLH ESVGLAAEIY EGSITDLPNP KAKKK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..475] PSI-BLAST 75.221849 STRUCTURE OF DIHYDROLIPOAMIDE DEHYDROGENASE

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • pyruvate dehydrogenase activity
    		•  6.59152030973708 bayes_pls_golite062009
  • oxidoreductase activity, acting on NADH or NADPH
    		•  6.01050580930819 bayes_pls_golite062009
  • dihydrolipoyl dehydrogenase activity
    		•  5.38255966064925 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor
    		•  5.18991258719053 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-NH2 group of donors
    		•  3.35142373392777 bayes_pls_golite062009
  • oxidoreductase activity
    		•  3.19495080984613 bayes_pls_golite062009
  • hydrogen ion transmembrane transporter activity
    		•  2.57282017498189 bayes_pls_golite062009
  • monovalent inorganic cation transmembrane transporter activity
    		•  2.50603438449246 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  2.3998060954585 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  2.38687908444458 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  2.35426029070392 bayes_pls_golite062009
  • inorganic cation transmembrane transporter activity
    		•  2.28982462439281 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  2.19095357354283 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  2.17217047087399 bayes_pls_golite062009
  • oxidoreductase activity, acting on the aldehyde or oxo group of donors
    		•  2.12515648558024 bayes_pls_golite062009
  • catalytic activity
    		•  1.56773888754354 bayes_pls_golite062009
  • antioxidant activity
    		•  1.49429830917872 bayes_pls_golite062009
  • oxygen-dependent protoporphyrinogen oxidase activity
    		•  1.42994468012845 bayes_pls_golite062009
  • thioredoxin-disulfide reductase activity
    		•  0.844975371289313 bayes_pls_golite062009
  • binding
    		•  0.794954996246594 bayes_pls_golite062009
  • NADPH-adrenodoxin reductase activity
    		•  0.684108511779641 bayes_pls_golite062009
  • transferase activity
    		•  0.565295320107724 bayes_pls_golite062009
  • electron carrier activity
    		•  0.511623955786613 bayes_pls_golite062009
  • coenzyme binding
    		•  0.424849261981 bayes_pls_golite062009
  • succinate dehydrogenase activity
    		•  0.110826254138262 bayes_pls_golite062009
  • protein binding
    		•  0.0171008177759692 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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