YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|24372021, gi\|...
Organism:	Shewanella oneidensis MR-1
Length:	475 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|24372021, gi|....

Description	E-value	Query Range	Subject Range
gi\|71062053, gi\|... - gi\|71082940\|ref\|YP_265659.1\| dihydrolipoyl dehydrogenase [Candidatus Pelagibacter ubique HTCC1062], ...	382.0	[0..1]	[466..1]
gi\|91762636, gi\|... - gi\|91762636\|ref\|ZP_01264601.1\| Dihydrolipoyl dehydrogenase [Candidatus Pelagibacter ubique HTCC1002]...	382.0	[0..1]	[466..1]
gi\|78688058, gi\|... - gi\|78688058\|ref\|ZP_00852783.1\| Dihydrolipoamide dehydrogenase [Shewanella sp. ANA-3], gi\|78504205\|gb...	381.0	[0..1]	[475..1]
gi\|113890526, gi... - gi\|78690757\|ref\|ZP_00855396.1\| Dihydrolipoamide dehydrogenase [Shewanella sp. MR-7], gi\|78509813\|gb\|...	380.0	[0..1]	[475..1]
gi\|113968774, gi... - gi\|82497171\|ref\|ZP_00882729.1\| Dihydrolipoamide dehydrogenase [Shewanella sp. MR-4], gi\|82404760\|gb\|...	380.0	[0..1]	[475..1]
gi\|69159567, gi\|... - gi\|91794729\|ref\|YP_564380.1\| dihydrolipoamide dehydrogenase [Shewanella denitrificans OS217], gi\|917...	377.0	[0..1]	[475..1]
gi\|114319433, gi... - gi\|78702851\|ref\|ZP_00867272.1\| Dihydrolipoamide dehydrogenase [Alkalilimnicola ehrlichei MLHE-1], gi...	376.0	[0..6]	[474..126]
gi\|120557452, gi... - gi\|82742201\|ref\|ZP_00904901.1\| Dihydrolipoamide dehydrogenase [Shewanella sp. W3-18-1], gi\|82720409\|... gi\|145566190, gi... - gi\|77813919\|ref\|ZP_00813190.1\| Dihydrolipoamide dehydrogenase [Shewanella putrefaciens CN-32], gi\|77...	376.0	[0..1]	[475..1]
gi\|69166560, gi\|... - gi\|69949936\|ref\|ZP_00637900.1\| Dihydrolipoamide dehydrogenase [Shewanella frigidimarina NCIMB 400], ...	376.0	[0..1]	[475..1]
gi\|68546238, gi\|... - gi\|68546238\|ref\|ZP_00585786.1\| Dihydrolipoamide dehydrogenase [Shewanella amazonensis SB2B], gi\|6851...	375.0	[0..1]	[475..1]

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Predicted Domain #1

Region A:
Residues: [1-475]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNEIKTQVV VLGAGPAGYS AAFRAADLGL ETVIVERFST LGGVCLNVGC IPSKALLHVA  60
   61 KVIEEAKAVA AHGVVFGEPT IDLDKLRSFK QKVISQLTGG LGGMSKMRKV NVVNGFGKFS 120
  121 GPNSLEVTAE DGTVTVVKFD QAIIAAGSRP IKLPFIPHED PRIWDSTDAL ELKEVPGKLL 180
  181 VMGGGIIGLE MGTVYSSLGS EIDVVEMFDQ VIPAADKDVV RVFTKQIKKK FNLILETKVT 240
  241 AVEAREDGIY VSMEGKSAPA EPVRYDAVLV AIGRTPNGKL IDAEKAGVKI DERGFINVDK 300
  301 QLRTNVPHIY AIGDIVGQPM LAHKGVHEGH VAAEVIAGMK HYFDPKVIPS IAYTDPEVAW 360
  361 VGLTEKEAKE QGIAYETATF PWAASGRAIA SDCSEGMTKL IFDKDTHRVI GGAIVGVNGG 420
  421 ELLGEIGLAI EMGCDAEDLA LTIHAHPTLH ESVGLAAEIY EGSITDLPNP KAKKK

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	75.221849
Match:	1ojtA
Description:	STRUCTURE OF DIHYDROLIPOAMIDE DEHYDROGENASE
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
pyruvate dehydrogenase activity	6.59152030973708	bayes_pls_golite062009
oxidoreductase activity, acting on NADH or NADPH	6.01050580930819	bayes_pls_golite062009
dihydrolipoyl dehydrogenase activity	5.38255966064925	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors, NAD or NADP as acceptor	5.18991258719053	bayes_pls_golite062009
oxidoreductase activity, acting on the CH-NH2 group of donors	3.35142373392777	bayes_pls_golite062009
oxidoreductase activity	3.19495080984613	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.57282017498189	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.50603438449246	bayes_pls_golite062009
cation transmembrane transporter activity	2.3998060954585	bayes_pls_golite062009
oxidoreductase activity, acting on sulfur group of donors	2.38687908444458	bayes_pls_golite062009
ion transmembrane transporter activity	2.35426029070392	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.28982462439281	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	2.19095357354283	bayes_pls_golite062009
substrate-specific transporter activity	2.17217047087399	bayes_pls_golite062009
oxidoreductase activity, acting on the aldehyde or oxo group of donors	2.12515648558024	bayes_pls_golite062009
catalytic activity	1.56773888754354	bayes_pls_golite062009
antioxidant activity	1.49429830917872	bayes_pls_golite062009
oxygen-dependent protoporphyrinogen oxidase activity	1.42994468012845	bayes_pls_golite062009
thioredoxin-disulfide reductase activity	0.844975371289313	bayes_pls_golite062009
binding	0.794954996246594	bayes_pls_golite062009
NADPH-adrenodoxin reductase activity	0.684108511779641	bayes_pls_golite062009
transferase activity	0.565295320107724	bayes_pls_golite062009
electron carrier activity	0.511623955786613	bayes_pls_golite062009
coenzyme binding	0.424849261981	bayes_pls_golite062009
succinate dehydrogenase activity	0.110826254138262	bayes_pls_golite062009
protein binding	0.0171008177759692	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: