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Protein Overview: VPS3_YEAST

General Information:
Name(s) found: VPS3_YEAST [Swiss-Prot]
Description(s) found:
  • Vacuolar protein sorting-associated protein 3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=VPS3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1011 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKKKTNNDK GKEVKENEGK LDIDSESSPH ERENDKKKTE DDSLRATESE ETNTHNANPN  60
   61 ETVRADKFSQ EESRPIEDSP HTDKNTAQES CQPSSAEDNV INTDITSLNE KTSTNDEQEK 120
  121 GLPLKISEGP FTISTLLDNV PSDLIYTCCE AYENHIFLGT TTGDLLHYFE LERGNYMLVS 180
  181 QTKFDAESNS KIDKILLLPK VEGALILCDN ELVLFILPEF APRPNTTRLK GISDVVICNF 240
  241 SRSSKAYRIY AFHAEGVRLL KISADSLVLT KAFNFKLIDK ACAHEETLMV SKLNSYELIN 300
  301 LKSSQVIPLF RISETDEDLE PIITSFNEQS EFLVCSGGGS YDSGAMALVV NHHGDIIKGT 360
  361 IVLKNYPRNV IVEFPYIIAE SAFQSVDIYS ALPSEKSQLL QSITTSGSDL KISKSDNVFT 420
  421 NTNNSEEFKE KIFNKLRLEP LTHSDNKFRI ERERAFVEES YEEKTSLIVY NNLGIHLLVP 480
  481 TPMVLRFTSC EESEIDNIED QLKKLAKKDL TKFEHIEAKY LMSLLLFLMT LHYDHIEDEV 540
  541 MKKWCDFSDK VDIRILFYMF GWKVYSEIWC FHGLINIVER LKSLKLTNKC ENILKMLLMM 600
  601 KNELKKKNKT GLLTNDFDDI MKTIDITLFK LRLEKKETIT VDMFERESYD EIIREINLHD 660
  661 DKLPRIELLI EIYKEKGEYL KALNLLREAG DYISLVSFIE ENLKKLPEDY IKERIADDLL 720
  721 LTLKQGDENT EECAIKKVLK ILDMACINKN DFLNKIPAEE TSLKVSFIEQ LGVQNSNDSK 780
  781 FLFNYYLAKL REIINQSNIW SILGDFIKEY KDDFAYDKTD ITNFIHIKLK HSLQCENFSK 840
  841 YYEKCENLKS ENEKDDEFIN FTFDEISKID KEHILTLLFF PNELTNWVSS EELLKIYLSF 900
  901 NDFRSVEKYI GKQNLVAVMK QYLDISSLNY SVELVTNLLQ RNFELLDDTD IQLKILETIP 960
  961 SVFPVQTISE LLLKVLIKYQ EKKEESNLRK CLLKNQISIS DELSRNFDSQ G

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..98] deduced N/A No confident structure predictions are available.
    2 View Details [99..726] MSA 15.038994 View MSA. No confident structure predictions are available.
    3 View Details [727..1011] deduced N/A No confident structure predictions are available.
    4 View Details [407..491] deduced N/A No confident structure predictions are available.
    5 View Details [492..1011] FFAS03 0.962 Clathrin heavy chain proximal leg segment

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.
    5
    Term Confidence Notes
  • protein transporter activity
    		•  2.99345877012947 bayes_pls_golite062009
  • binding
    		•  2.33303322187387 bayes_pls_golite062009
  • transporter activity
    		•  1.85346023606579 bayes_pls_golite062009
  • substrate-specific transporter activity
    		•  1.51565516399356 bayes_pls_golite062009
  • protein binding
    		•  1.5114863464349 bayes_pls_golite062009
  • protein transmembrane transporter activity
    		•  1.12112006227201 bayes_pls_golite062009
  • transmembrane transporter activity
    		•  0.710528717985301 bayes_pls_golite062009
  • proton-transporting ATPase activity, rotational mechanism
    		•  0.68860343348996 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.39311980867126 bayes_pls_golite062009
  • signal sequence binding
    		•  0.279693431859311 bayes_pls_golite062009
  • nuclear localization sequence binding
    		•  0.241630311762028 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.170608604167104 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
    		•  0.109435859778099 bayes_pls_golite062009
  • pyrophosphatase activity
    		•  0.0728493557966827 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides
    		•  0.0641324729536009 bayes_pls_golite062009
  • hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides
    		•  0.0615190129942244 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle