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Protein Overview: TOS3_YEAST

General Information:
Name(s) found: TOS3_YEAST [Swiss-Prot]
Description(s) found:
  • Serine/threonine-protein kinase TOS3 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=TOS3 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 560 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVLLKEPVQP LPRSSLLYNN ASNSSSRIKE TRKVKLLYNP LTKRQILNNF EILATLGNGQ  60
   61 YGKVKLARDL GTGALVAIKI LNRFEKRSGY SLQLKVENPR VNQEIEVMKR CHHENVVELY 120
  121 EILNDPESTK VYLVLEYCSR GPVKWCPENK MEIKAVGPSI LTFQQSRKVV LDVVSGLEYL 180
  181 HSQGITHRDI KPSNLLISSN GTVKISDFGV AMSTATGSTN IQSSHEQLLK SRALGTPAFF 240
  241 APELCSTEKE YSCSSAIDIW SLGVTIYCLL FGKLPFNANS GLELFDSIIN KPLEFPSYEE 300
  301 MLNGATSGIT MEEYTDAKDL LKKLLQKDPD KRIKLADIKV HPFMCHYGKS DAASVLTNLE 360
  361 TFHELKVSPP SSCKRVELVS LPVNSSFASL DSVYMENFDH NNLRTGADRN STYSPSIYDA 420
  421 NTLSPSAYHN IGSRESSYSS FSSFTSSTAF ASQISIQDAP AIGDQQCLIG ESGSSLRVNS 480
  481 CEFPQYTTMS PVGEYPFEST EASLSSTLTP VGNVPQRIKA HLVEGKSNSK DDLRIEADAS 540
  541 LVFEASDAQR TRRRMSLYKL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..41]
    [97..119]
    [137..390]    		 PSI-BLAST 380.0 cAMP-dependent PK, catalytic subunit
    2 View Details [42..96]
    [120..136]
    [391..439]    		 PSI-BLAST 380.0 cAMP-dependent PK, catalytic subunit
    3 View Details [440..560] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • protein kinase activity
    		•  5.17195961442593 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  5.04467222534257 bayes_pls_golite062009
  • kinase activity
    		•  4.85903980916957 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  4.46381887831481 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.46123870227889 bayes_pls_golite062009
  • transferase activity
    		•  3.26787750561728 bayes_pls_golite062009
  • binding
    		•  2.31930216202447 bayes_pls_golite062009
  • ATP binding
    		•  1.97600611746091 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.90928021591891 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.65726906484847 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
    		•  1.63195828048121 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.3898059094397 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.38496328649031 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  1.27291233344322 bayes_pls_golite062009
  • protein binding
    		•  1.22565748038754 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.393328812780268 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.282849280638519 bayes_pls_golite062009
  • signal transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.270054246024761 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.0556163711947139 bayes_pls_golite062009
  • transmembrane receptor activity
    		•  0.00652065412910241 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle