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Protein Overview: SIS2_YEAST

General Information:
Name(s) found: SIS2_YEAST [Swiss-Prot]
Description(s) found:
  • Phosphopantothenoylcysteine decarboxylase subunit SIS2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=SIS2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTAVASTSGK QDADHNQSIE CPRFSRGQKE ILLDHEDAKG KDSIINSPVS GRQSISPTLS  60
   61 NATTTTTKSI MNATGTSGAV VSNTPEPGLK RVPAVTFSDL KQQQKQDSLT QLKNDSERTK 120
  121 SPNSNPAPVS NSIPGNHAVI PNHTNTSRTT QLSGSPLVNE MKDYDPKKKD SALKIVDTMK 180
  181 PDKIMATSTP ISRENNKVTA KAPTSITLRK EDAQDQANNV SGQINVRSTP EETPVKQSVI 240
  241 PSIIPKRENS KNLDPRLPQD DGKLHVLFGA TGSLSVFKIK PMIKKLEEIY GRDRISIQVI 300
  301 LTQSATQFFE QRYTKKIIKS SEKLNKMSQY ESTPATPVTP TPGQCNMAQV VELPPHIQLW 360
  361 TDQDEWDAWK QRTDPVLHIE LRRWADILVV APLTANTLSK IALGLCDNLL TSVIRAWNPS 420
  421 YPILLAPSMV SSTFNSMMTK KQLQTIKEEM SWVTVFKPSE KVMDINGDIG LGGMMDWNEI 480
  481 VNKIVMKLGG YPKNNEEEDD DEDEEEDDDE EEDTEDKNEN NNDDDDDDDD DDDDDDDDDD 540
  541 DDDDDDEDED EAETPGIIDK HQ

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..283] MSA 80.222997 View MSA. No confident structure predictions are available.
    2 View Details [284..562] PSI-BLAST 371.274545 4'-phosphopantothenoylcysteine decarboxylase (PPC decarboxylase, halotolerance protein Hal3a)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphopantothenoylcysteine decarboxylase activity
    		•  3.86093811191169 bayes_pls_golite062009
  • phosphopantothenate--cysteine ligase activity
    		•  2.64345867885176 bayes_pls_golite062009
  • binding
    		•  1.79334633421708 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.79168084682693 bayes_pls_golite062009
  • catalytic activity
    		•  1.51672397362026 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.03827559540394 bayes_pls_golite062009
  • protein binding
    		•  0.359358565373414 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle