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Protein Overview: NOP2_YEAST

General Information:
Name(s) found: NOP2_YEAST [Swiss-Prot]
Description(s) found:
  • 25S rRNA (cytosine(2870)-C(5))-methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOP2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 618 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSRRHKNKQ AAPPTLEEFQ ARKEKKANRK LEKGKRPSTT QGDEVSDRKK KKSKPFKKSR  60
   61 KEEEEVVEED KDLPEVDLEE LSKARKSLFD DEEDDDEAGL VDEELKDEFD LEQEYDYDED 120
  121 EDNDAHPIFS DDDDEADLEE LNAQNMEALS KKLDEEEAEE AEEAEMELVE AENMQPRADI 180
  181 LPTEEQEEMM AQETPNLTST RTRMIEIVKV LENFKTLGAE GRSRGEYVDR LLKDICEYFG 240
  241 YTPFLAEKLF NLFSPAEAME FFEANEIARP ITIRTNTLKT RRRDLAQTLV NRGVNLQPIG 300
  301 SWTKVGLQIF DSQVPIGATP EYLAGHYILQ AASSFLPVIA LDPHENERIL DMAAAPGGKT 360
  361 TYISAMMKNT GCVFANDANK SRTKSLIANI HRLGCTNTIV CNYDAREFPK VIGGFDRILL 420
  421 DAPCSGTGVI GKDQSVKVSR TEKDFIQIPH LQKQLLLSAI DSVDCNSKHG GVIVYSTCSV 480
  481 AVEEDEAVID YALRKRPNVK LVDTGLAIGK EAFTSYRGKK FHPSVKLARR YYPHTYNVDG 540
  541 FFVAKFQKIG PSSFDDNQAS AKEKETAARK EALEEGIIHS DFATFEDEED DKYIEKSVKN 600
  601 NLLKKGVNPK AKRPSNEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..215] MSA 28.071997 View MSA. No confident structure predictions are available.
    2 View Details [216..311] MSA 3.163984 View MSA. No confident structure predictions are available.
    3 View Details [312..618] PSI-BLAST 270.917458 No description for 1j4fA_ was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • rRNA (guanine) methyltransferase activity
    		•  3.42580501977103 bayes_pls_golite062009
  • S-adenosylmethionine-dependent methyltransferase activity
    		•  3.15840198589582 bayes_pls_golite062009
  • methyltransferase activity
    		•  3.08059259177729 bayes_pls_golite062009
  • transferase activity, transferring one-carbon groups
    		•  2.99781997782052 bayes_pls_golite062009
  • rRNA methyltransferase activity
    		•  2.89157295612945 bayes_pls_golite062009
  • RNA methyltransferase activity
    		•  2.57273894921779 bayes_pls_golite062009
  • N-methyltransferase activity
    		•  2.26670816231281 bayes_pls_golite062009
  • RNA binding
    		•  1.99752836873461 bayes_pls_golite062009
  • tRNA methyltransferase activity
    		•  1.55242772787972 bayes_pls_golite062009
  • catalytic activity
    		•  1.25333584501255 bayes_pls_golite062009
  • transferase activity
    		•  1.07321114919891 bayes_pls_golite062009
  • rRNA (adenine) methyltransferase activity
    		•  1.03293084629981 bayes_pls_golite062009
  • rRNA (adenine-N6,N6-)-dimethyltransferase activity
    		•  0.954020631547781 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.914549843668268 bayes_pls_golite062009
  • DNA binding
    		•  0.86027591375666 bayes_pls_golite062009
  • rRNA (uridine) methyltransferase activity
    		•  0.742142092552002 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.616949327277483 bayes_pls_golite062009
  • binding
    		•  0.383237930789959 bayes_pls_golite062009
  • rRNA (uridine-2'-O-)-methyltransferase activity
    		•  0.15443733645953 bayes_pls_golite062009
  • mRNA binding
    		•  0.0540207721800283 bayes_pls_golite062009
  • snoRNA binding
    		•  0.00848192089639488 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle