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Protein Overview: NOB1_YEAST

General Information:
Name(s) found: NOB1_YEAST [Swiss-Prot]
Description(s) found:
  • 20S-pre-rRNA D-site endonuclease NOB1 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NOB1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 459 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTENQTAHVR ALILDATPLI TQSYTHYQNY AQSFYTTPTV FQEIKDAQAR KNLEIWQSLG  60
   61 TLKLVHPSEN SIAKVSTFAK LTGDYSVLSA NDLHILALTY ELEIKLNNGD WRLRKKPGDA 120
  121 LDASKADVGT DGKQKLTEDN KKEEDSESVP KKKNKRRGGK KQKAKREARE AREAENANLE 180
  181 LESKAEEHVE EAGSKEQICN DENIKESSDL NEVFEDADDD GDWITPENLT EAIIKDSGED 240
  241 TTGSLGVEAS EEDRHVALNR PENQVALATG DFAVQNVALQ MNLNLMNFMS GLKIKRIRNY 300
  301 MLRCHACFKI FPLPKDGKPK HFCASCGGQG TLLRCAVSVD SRTGNVTPHL KSNFQWNNRG 360
  361 NRYSVASPLS KNSQKRYGKK GHVHSKPQEN VILREDQKEY EKVIKQEEWT RRHNEKILNN 420
  421 WIGGGSADNY ISPFAITGLK QHNVRIGKGR YVNSSKRRS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..177] MSA 15.041993 View MSA. No confident structure predictions are available.
    2 View Details [178..459] MSA 1.015926 View MSA. No confident structure predictions are available.
    3 View Details [223..386] PSI-BLAST 23.0 Solution Structure of RSGI RUH-035, a Zn-ribbon module in Mouse cDNA
    4 View Details [387..459] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • nuclease activity
    		•  2.0989149357263 bayes_pls_golite062009
  • DNA binding
    		•  1.98330542087379 bayes_pls_golite062009
  • binding
    		•  1.91435224223408 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.86243238793767 bayes_pls_golite062009
  • exonuclease activity
    		•  1.7620419369992 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  1.74349203224875 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  1.68760157046614 bayes_pls_golite062009
  • endonuclease activity
    		•  1.2840172881923 bayes_pls_golite062009
  • catalytic activity
    		•  1.27951740231695 bayes_pls_golite062009
  • flap endonuclease activity
    		•  1.17726395799783 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.07360773846975 bayes_pls_golite062009
  • 5'-3' exonuclease activity
    		•  0.974028111038185 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.867731336605067 bayes_pls_golite062009
  • hydrolase activity
    		•  0.827276601361763 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.79417076649627 bayes_pls_golite062009
  • protein binding
    		•  0.695466920831325 bayes_pls_golite062009
  • exodeoxyribonuclease activity, producing 5'-phosphomonoesters
    		•  0.267787854683683 bayes_pls_golite062009
  • exodeoxyribonuclease activity
    		•  0.260397221344929 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • RNA binding
    		•  2.67504868533195 bayes_pls_golite062009
  • binding
    		•  2.1226043957694 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.26170105245043 bayes_pls_golite062009
  • protein binding
    		•  0.874974846355882 bayes_pls_golite062009
  • catalytic activity
    		•  0.316629025709297 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle