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Protein Overview: NMD2_YEAST

General Information:
Name(s) found: NMD2_YEAST [Swiss-Prot]
Description(s) found:
  • Nonsense-mediated mRNA decay protein 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=NMD2 PE=1 SV=2 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1089 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDGRKKELH DLNTRAWNGE EVFPLKSKKL DSSIKRNTGF IKKLKKGFVK GSESSLLKDL  60
   61 SEASLEKYLS EIIVTVTECL LNVLNKNDDV IAAVEIISGL HQRFNGRFTS PLLGAFLQAF 120
  121 ENPSVDIESE RDELQRITRV KGNLRVFTEL YLVGVFRTLD DIESKDAIPN FLQKKTGRKD 180
  181 PLLFSILREI LNYKFKLGFT TTIATAFIKK FAPLFRDDDN SWDDLIYDSK LKGALQSLFK 240
  241 NFIDATFARA TELHKKVNKL QREHQKCQIR TGKLRDEYVE EYDKLLPIFI RFKTSAITLG 300
  301 EFFKLEIPEL EGASNDDLKE TASPMITNQI LPPNQRLWEN EDTRKFYEIL PDISKTVEES 360
  361 QSSKTEKDSN VNSKNINLFF TDLEMADCKD IIDDLSNRYW SSYLDNKATR NRILKFFMET 420
  421 QDWSKLPVYS RFIATNSKYM PEIVSEFINY LDNGFRSQLH SNKINVKNII FFSEMIKFQL 480
  481 IPSFMIFHKI RTLIMYMQVP NNVEILTVLL EHSGKFLLNK PEYKELMEKM VQLIKDKKND 540
  541 RQLNMNMKSA LENIITLLYP PSVKSLNVTV KTITPEQQFY RILIRSELSS LDFKHIVKLV 600
  601 RKAHWDDVAI QKVLFSLFSK PHKISYQNIP LLTKVLGGLY SYRRDFVIRC IDQVLENIER 660
  661 GLEINDYGQN MHRISNVRYL TEIFNFEMIK SDVLLDTIYH IIRFGHINNQ PNPFYLNYSD 720
  721 PPDNYFRIQL VTTILLNINR TPAAFTKKCK LLLRFFEYYT FIKEQPLPKE TEFRVSSTFK 780
  781 KYENIFGNTK FERSENLVES ASRLESLLKS LNAIKSKDDR VKGSSASIHN GKESAVPIES 840
  841 ITEDDEDEDD ENDDGVDLLG EDEDAEISTP NTESAPGKHQ AKQDESEDED DEDDDEDDDD 900
  901 DDDDDDDDGE EGDEDDDEDD DDEDDDDEEE EDSDSDLEYG GDLDADRDIE MKRMYEEYER 960
  961 KLKDEEERKA EEELERQFQK MMQESIDARK SEKVVASKIP VISKPVSVQK PLLLKKSEEP1020
 1021 SSSKETYEEL SKPKKIAFTF LTKSGKKTQS RILQLPTDVK FVSDVLEEEE KLKTERNKIK1080
 1081 KIVLKRSFD

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..272] Pfam 28.070581 MIF4G domain No confident structure predictions are available.
    2 View Details [273..336] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [337..589] ORFEUS 13.8 CBP80, 80KDa nuclear cap-binding protein
    4 View Details [590..944] PSI-BLAST 48.522879 Heavy meromyosin subfragment
    5 View Details [945..1089] PSI-BLAST 17.221849 Tropomyosin

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • RNA binding
    		•  4.05046860305563 bayes_pls_golite062009
  • mRNA binding
    		•  2.35042158577052 bayes_pls_golite062009
  • binding
    		•  1.72811847650743 bayes_pls_golite062009
  • protein binding
    		•  1.3800948965226 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.916304573557693 bayes_pls_golite062009
  • structural molecule activity
    		•  0.867897004862886 bayes_pls_golite062009
  • RNA cap binding
    		•  0.357520253345298 bayes_pls_golite062009
  • hydrolase activity
    		•  0.33256091835104 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.0462205765670426 bayes_pls_golite062009
    4
    Term Confidence Notes
  • RNA binding
    		•  4.20683443264388 bayes_pls_golite062009
  • mRNA binding
    		•  2.49094746544717 bayes_pls_golite062009
  • binding
    		•  1.83406697369076 bayes_pls_golite062009
  • protein binding
    		•  1.50566694420704 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.967597910409065 bayes_pls_golite062009
  • structural molecule activity
    		•  0.868289396026548 bayes_pls_golite062009
  • RNA cap binding
    		•  0.66277586901495 bayes_pls_golite062009
  • hydrolase activity
    		•  0.29428275639657 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.022274123463527 bayes_pls_golite062009
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle