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Protein Overview: METE_YEAST

General Information:
Name(s) found: METE_YEAST [Swiss-Prot]
Description(s) found:
  • 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=MET6 PE=1 SV=4 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 767 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQSAVLGFP RIGPNRELKK ATEGYWNGKI TVDELFKVGK DLRTQNWKLQ KEAGVDIIPS  60
   61 NDFSFYDQVL DLSLLFNVIP DRYTKYDLSP IDTLFAMGRG LQRKATETEK AVDVTALEMV 120
  121 KWFDSNYHYV RPTFSKTTQF KLNGQKPVDE FLEAKELGIH TRPVLLGPVS YLFLGKADKD 180
  181 SLDLEPLSLL EQLLPLYTEI LSKLASAGAT EVQIDEPVLV LDLPANAQAA IKKAYTYFGE 240
  241 QSNLPKITLA TYFGTVVPNL DAIKGLPVAA LHVDFVRAPE QFDEVVAAIG NKQTLSVGIV 300
  301 DGRNIWKNDF KKSSAIVNKA IEKLGADRVV VATSSSLLHT PVDLNNETKL DAEIKGFFSF 360
  361 ATQKLDEVVV ITKNVSGQDV AAALEANAKS VESRGKSKFI HDAAVKARVA SIDEKMSTRA 420
  421 APFEQRLPEQ QKVFNLPLFP TTTIGSFPQT KDIRINRNKF NKGTISAEEY EKFINSEIEK 480
  481 VIRFQEEIGL DVLVHGEPER NDMVQYFGEQ INGYAFTVNG WVQSYGSRYV RPPIIVGDLS 540
  541 RPKAMSVKES VYAQSITSKP VKGMLTGPIT CLRWSFPRDD VDQKTQAMQL ALALRDEVND 600
  601 LEAAGIKVIQ VDEPALREGL PLREGTERSA YYTWAAEAFR VATSGVANKT QIHSHFCYSD 660
  661 LDPNHIKALD ADVVSIEFSK KDDANYIAEF KNYPNHIGLG LFDIHSPRIP SKDEFIAKIS 720
  721 TILKSYPAEK FWVNPDCGLK TRGWEETRLS LTHMVEAAKY FREQYKN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..104] MSA 1.042975 View MSA. No confident structure predictions are available.
    2 View Details [105..401] deduced N/A No confident structure predictions are available.
    3 View Details [402..440]
    [674..767]    		 ORFEUS 11.96 Uroporphyrinogen decarboxylase, UROD
    4 View Details [441..673] ORFEUS 11.96 Uroporphyrinogen decarboxylase, UROD

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • 5-methyltetrahydropteroyltriglutamate-homocysteine S-methyltransferase activity
    		•  6.40786073037099 bayes_pls_golite062009
  • 5-methyltetrahydropteroyltri-L-glutamate-dependent methyltransferase activity
    		•  6.40786073037099 bayes_pls_golite062009
  • uroporphyrinogen decarboxylase activity
    		•  3.13638443707338 bayes_pls_golite062009
  • S-methyltransferase activity
    		•  3.0142199413027 bayes_pls_golite062009
  • catalytic activity
    		•  2.37862248560593 bayes_pls_golite062009
  • binding
    		•  1.590130518929 bayes_pls_golite062009
  • carbon-carbon lyase activity
    		•  1.54242506764415 bayes_pls_golite062009
  • carboxy-lyase activity
    		•  1.52150758949987 bayes_pls_golite062009
  • lyase activity
    		•  0.825209465219608 bayes_pls_golite062009
  • protein binding
    		•  0.21865699924356 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle