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Protein Overview: KICH_YEAST

General Information:
Name(s) found: KICH_YEAST [Swiss-Prot]
Description(s) found:
  • Choline kinase OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=CKI1 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 582 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVQESRPGSV RSYSVGYQAR SRSSSQRRHS LTRQRSSQRL IRTISIESDV SNITDDDDLR  60
   61 AVNEGVAGVQ LDVSETANKG PRRASATDVT DSLGSTSSEY IEIPFVKETL DASLPSDYLK 120
  121 QDILNLIQSL KISKWYNNKK IQPVAQDMNL VKISGAMTNA IFKVEYPKLP SLLLRIYGPN 180
  181 IDNIIDREYE LQILARLSLK NIGPSLYGCF VNGRFEQFLE NSKTLTKDDI RNWKNSQRIA 240
  241 RRMKELHVGV PLLSSERKNG SACWQKINQW LRTIEKVDQW VGDPKNIENS LLCENWSKFM 300
  301 DIVDRYHKWL ISQEQGIEQV NKNLIFCHND AQYGNLLFTA PVMNTPSLYT APSSTSLTSQ 360
  361 SSSLFPSSSN VIVDDIINPP KQEQSQDSKL VVIDFEYAGA NPAAYDLANH LSEWMYDYNN 420
  421 AKAPHQCHAD RYPDKEQVLN FLYSYVSHLR GGAKEPIDEE VQRLYKSIIQ WRPTVQLFWS 480
  481 LWAILQSGKL EKKEASTAIT REEIGPNGKK YIIKTEPESP EEDFVENDDE PEAGVSIDTF 540
  541 DYMAYGRDKI AVFWGDLIGL GIITEEECKN FSSFKFLDTS YL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..143] deduced N/A No confident structure predictions are available.
    2 View Details [144..191]
    [205..218]    		 ORFEUS 12.95 Type IIIa 3',5"-aminoglycoside phosphotransferase
    3 View Details [192..204]
    [219..363]    		 ORFEUS 12.95 Type IIIa 3',5"-aminoglycoside phosphotransferase
    4 View Details [364..519] MSA 1.049982 View MSA. No confident structure predictions are available.
    5 View Details [520..582] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • phosphotransferase activity, alcohol group as acceptor
    		•  4.77705138922602 bayes_pls_golite062009
  • protein kinase activity
    		•  4.68131600649845 bayes_pls_golite062009
  • kinase activity
    		•  4.63102094866388 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.26470104655954 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.92556971928915 bayes_pls_golite062009
  • transferase activity
    		•  3.27487631214089 bayes_pls_golite062009
  • binding
    		•  2.31186607166478 bayes_pls_golite062009
  • ATP binding
    		•  1.62950013799854 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.59120412984243 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.57251948653832 bayes_pls_golite062009
  • lipid kinase activity
    		•  1.3504796246251 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.32931505255952 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.32676572752438 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.31489723493061 bayes_pls_golite062009
  • nucleotide binding
    		•  1.31339663939554 bayes_pls_golite062009
  • protein binding
    		•  1.24858883313437 bayes_pls_golite062009
  • catalytic activity
    		•  1.21655087018101 bayes_pls_golite062009
  • choline kinase activity
    		•  1.18757364210199 bayes_pls_golite062009
  • phosphoinositide 3-kinase activity
    		•  1.10484220525143 bayes_pls_golite062009
  • protein tyrosine kinase activity
    		•  1.06634272225692 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
    		•  1.05231366895645 bayes_pls_golite062009
  • 1-phosphatidylinositol-3-kinase activity
    		•  1.04034573968654 bayes_pls_golite062009
  • inositol or phosphatidylinositol kinase activity
    		•  0.97254836668426 bayes_pls_golite062009
  • receptor signaling protein activity
    		•  0.957217569601377 bayes_pls_golite062009
  • ethanolamine kinase activity
    		•  0.68804237112665 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
    		•  0.380769480509274 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
    		•  0.22871167092767 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
    		•  0.185842548207239 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.134745748018448 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
    		•  0.0569871200546399 bayes_pls_golite062009
  • MAP kinase kinase activity
    		•  0.04117702615323 bayes_pls_golite062009
    3 No functions predicted.
    4 No functions predicted.
    5 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle