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Protein Overview: HOS4_YEAST

General Information:
Name(s) found: HOS4_YEAST [Swiss-Prot]
Description(s) found:
  • Protein HOS4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=HOS4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1083 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNETTTKQPL KKRSLSSYLS NVSTRREELE KISKQETSEE EDTAGKHEQR ETLSEEVSDK  60
   61 FPENVASFRS QTTSVHQATQ NNLNAKESED LAHKNDASSH EGEVNGDSRP DDVPETNEKI 120
  121 SQAIRAKISS SSSSPNVRNV DIQNHQPFSR DQLRAMLKEP KRKTVDDFIE EEGLGAVEEE 180
  181 DLSDEVLEKN TTEPENVEKD IEYSDSDKDT DDVGSDDPTA PNSPIKLGRR KLVRGDQLDA 240
  241 TTSSMFNNES DSELSDIDDS KNIALSSSLF RGGSSPVKET NNNLSNMNSS PAQNPKRGSV 300
  301 SRSNDSNKSS HIAVSKRPKQ KKGIYRDSGG RTRLQIACDK GKYDVVKKMI EEGGYDINDQ 360
  361 DNAGNTALHE AALQGHIEIV ELLIENGADV NIKSIEMFGD TPLIDASANG HLDVVKYLLK 420
  421 NGADPTIRNA KGLTAFESVD DESEFDDEED QKILREIKKR LSIAAKKWTN RAGIHNDKSK 480
  481 NGNNAHTIDQ PPFDNTTKAK NEKAADSPSM ASNIDEKAPE EEFYWTDVTS RAGKEKLFKA 540
  541 SKEGHLPYVG TYVENGGKID LRSFFESVKC GHEDITSIFL AFGFPVNQTS RDNKTSALMV 600
  601 AVGRGHLGTV KLLLEAGADP TKRDKKGRTA LYYAKNSIMG ITNSEEIQLI ENAINNYLKK 660
  661 HSEDNNDDDD DDDNNNETYK HEKKREKTQS PILASRRSAT PRIEDEEDDT RMLNLADDDF 720
  721 NNDRDVKEST TSDSRKRLDD NENVGTQYSL DWKKRKTNAL QDEEKLKSIS PLSMEPHSPK 780
  781 KAKSVEISKI HEETAAEREA RLKEEEEYRK KRLEKKRKKE QELLQKLAED EKKRIEEQEK 840
  841 QKVLEMERLE KATLEKARKM EREKEMEEIS YRRAVRDLYP LGLKIINFND KLDYKRFLPL 900
  901 YYFVDEKNDK FVLDLQVMIL LKDIDLLSKD NQPTSEKIPV DPSHLTPLWN MLKFIFLYGG 960
  961 SYDDKKNNME NKRYVVNFDG VDLDTKIGYE LLEYKKFVSL PMAWIKWDNV VIENHAKRKE1020
 1021 IEGNMIQISI NEFARWRNDK LNKAQQPTRK QRSLKIPREL PVKFQHRMSI SSVLQQTSKE1080
 1081 PFW

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..202] MSA 2.237994 View MSA. No confident structure predictions are available.
    2 View Details [203..301] PSI-BLAST 73.67837 p18ink4C(ink6)
    3 View Details [302..388] PSI-BLAST 73.67837 p18ink4C(ink6)
    4 View Details [389..481] PSI-BLAST 111.9897 GA bindinig protein (GABP) beta 1
    5 View Details [482..557] MSA 3.516997 View MSA. No confident structure predictions are available.
    6 View Details [558..625] PSI-BLAST 134.29073 Myotrophin
    7 View Details [626..678] PSI-BLAST 134.29073 Myotrophin
    8 View Details [679..939] ORFEUS 11.83 No description for 1ldvA was found.
    9 View Details [940..1083] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • binding
    		•  2.60916417202222 bayes_pls_golite062009
  • protein binding
    		•  1.64872738860757 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  1.39841714205637 bayes_pls_golite062009
  • structural constituent of cytoskeleton
    		•  0.89889442280136 bayes_pls_golite062009
  • transcription factor binding
    		•  0.84590123339816 bayes_pls_golite062009
  • structural molecule activity
    		•  0.808967137205604 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
    		•  0.68541709976608 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.589753112911856 bayes_pls_golite062009
  • protein kinase regulator activity
    		•  0.576422771673579 bayes_pls_golite062009
  • histone methyltransferase activity
    		•  0.457348070377128 bayes_pls_golite062009
  • kinase regulator activity
    		•  0.4228431685549 bayes_pls_golite062009
  • protein kinase activity
    		•  0.348635473808088 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.280340492381105 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.144979134227429 bayes_pls_golite062009
  • DNA binding
    		•  0.139886855398905 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.108244697820437 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  0.0107560517063403 bayes_pls_golite062009
    4 No functions predicted.
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.
    8 No functions predicted.
    9 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle