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Protein Overview: GIN4_YEAST

General Information:
Name(s) found: GIN4_YEAST [Swiss-Prot]
Description(s) found:
  • Serine/threonine-protein kinase GIN4 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GIN4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 1142 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAINGNSIPA IKDNTIGPWK LGETLGLGST GKVQLARNGS TGQEAAVKVI SKAVFNTGNV  60
   61 SGTSIVGSTT PDALPYGIER EIIIMKLLNH PNVLRLYDVW ETNTDLYLVL EYAEKGELFN 120
  121 LLVERGPLPE HEAIRFFRQI IIGVSYCHAL GIVHRDLKPE NLLLDHKYNI KIADFGMAAL 180
  181 ETEGKLLETS CGSPHYAAPE IVSGIPYQGF ASDVWSCGVI LFALLTGRLP FDEEDGNIRT 240
  241 LLLKVQKGEF EMPSDDEISR EAQDLIRKIL TVDPERRIKT RDILKHPLLQ KYPSIRDSKS 300
  301 IRGLPREDTY LTPLSESNSS IDATILQNLV ILWHGRDPEG IKEKLREPGA NAEKTLYALL 360
  361 YRFKCDTQKE LIKQQQVKKR QSISSVSVSP SKKVSTTPQR RRNRESLISV TSSRKKPISF 420
  421 NKFTASSASS SNLTTPGSSK RLSKNFSSKK KLSTIVNQSS PTPASRNKRA SVINVEKNQK 480
  481 RASIFSTTKK NKRSSRSIKR MSLIPSMKRE SVTTKLMSTY AKLAEDDDWE YIEKETKRTS 540
  541 SNFATLIDEI FEYEKYEQIR KEKEELERKV REAKAREELE RRRRKQEEKE RARKLLEKED 600
  601 LKRKQEELKK QIEIDISDLE QELSKHKEEK LDGNIRSISA PMENEEKNIN HLEVDIDNIL 660
  661 RRRNFSLQTR PVSRLDPGIM FSSPTEEVSP VEPKRTENER LTTEKKILET IRRSKFLGSS 720
  721 FNIDKELKLS KMEYPSIIAP QRLSEERVVS DSNDGYESLI LPKDGNGVSQ LKDSTATTAP 780
  781 VSDGRLRKIS EIRVPQFTRK SRHFSESNKR LSVLSMYSTK ESFTNLVDIL KNGNLDVNNQ 840
  841 QSQRIPTPRS ADDSEFLFET VNEEAEYTGN SSNDERLYDV GDSTIKDKSA LKLNFADRFN 900
  901 GSNEAKQTDN LHLPILPPLN GDNELRKQNS QEGDQAHPKI KSMIPESGSS SHTEKEEENE 960
  961 EKEEKKPEQH KQEEDQEKRE KVVDDMEPPL NKSVQKIREK NAGSQAKDHS KDHLKEHKQD1020
 1021 KNTAIGNGSF FRKFSKSSDK TMELYAKISA KQLFNGLEKL LRGWTQYGLK NIKSHPNNLT1080
 1081 LTGKLSSDNI FSLRSTLFEV NIYPRGKMSV VQFKKVSGSF KAVKKLVNEV ENVLNKEGVL1140
 1141 QK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..115]
    [314..371]    		 PSI-BLAST 587.9897 Calmodulin-dependent protein kinase
    2 View Details [116..313] PSI-BLAST 587.9897 Calmodulin-dependent protein kinase
    3 View Details [372..1142] deduced N/A No confident structure predictions are available.
    4 View Details [613..690] PSI-BLAST 14.522879 Solution structure of kinase associated domain 1 of mouse MAP/microtubule affinity-regulating kinase 3
    5 View Details [691..749] deduced N/A No confident structure predictions are available.
    6 View Details [750..960] deduced N/A No confident structure predictions are available.
    7 View Details [961..1142] deduced N/A No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3 No functions predicted.
    4
    Term Confidence Notes
  • protein kinase activity
    		•  4.05475891009228 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  3.7974128326421 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  3.59230737331367 bayes_pls_golite062009
  • kinase activity
    		•  3.41737435609334 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  3.2342722637405 bayes_pls_golite062009
  • binding
    		•  2.41732321506551 bayes_pls_golite062009
  • transferase activity
    		•  2.04713540681686 bayes_pls_golite062009
  • ATP binding
    		•  1.44435058039859 bayes_pls_golite062009
  • adenyl ribonucleotide binding
    		•  1.41005152726625 bayes_pls_golite062009
  • adenyl nucleotide binding
    		•  1.38971642420542 bayes_pls_golite062009
  • ribonucleotide binding
    		•  1.16863558166547 bayes_pls_golite062009
  • purine ribonucleotide binding
    		•  1.16859376715941 bayes_pls_golite062009
  • purine nucleotide binding
    		•  1.15633908642115 bayes_pls_golite062009
  • nucleotide binding
    		•  1.14964488472581 bayes_pls_golite062009
  • catalytic activity
    		•  0.836142537655721 bayes_pls_golite062009
  • protein binding
    		•  0.704339182896017 bayes_pls_golite062009
  • AMP-activated protein kinase activity
    		•  0.496765880715405 bayes_pls_golite062009
  • magnesium ion binding
    		•  0.439688030503848 bayes_pls_golite062009
    5 No functions predicted.
    6 No functions predicted.
    7 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle