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Protein Overview: EI2BD_YEAST

General Information:
Name(s) found: EI2BD_YEAST [Swiss-Prot]
Description(s) found:
  • Translation initiation factor eIF-2B subunit delta OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=GCD2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 651 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSESEAKSRS ATPPSKAKQA TPTTTAAANG EKKLTNKELK ELKKQEKAAK RAAMKQANGI  60
   61 SIEQQQQQAQ MKKEKKQLQR EQQQKREQKQ KNANKKKQNE RNVKKSTLFG HLETTEERRA 120
  121 TILALTSAVS SPKTSRITAA GLMVPVVASA LSGSNVLTAS SLMPVGPNAS STVSASAPAS 180
  181 TTTTLPASSA ALSAGTSSAS TNTPTAIQQE IASSNASDVA KTLASISLEA GEFNVIPGIS 240
  241 SVIPTVLEQS FDNSSLISSV KELLLNKDLI HPSILLLTSH LAHYKIVGSI PRCIAMLEVF 300
  301 QIVIKDYQTP KGTTLSRNLT SYLSHQIDLL KKARPLSVTM GNAIRWLKQE ISLIDPSTPD 360
  361 KAAKKDLCEK IGQFAKEKIE LADQLIIDNA STQIEESTTI VTYGSSKVLT ELLLHNAISL 420
  421 KKNIKVIVVD SRPLFEGRKM AETLRNAGVN VMYALITSLD TIFNMDVDYV FLGAHSILSN 480
  481 GFLYSRAGTA MLAMSAKRRN IPVLVCCESL KFSQRVQLDS VTFNELADPN DLVNIDYENP 540
  541 VERRGNKGAL LNQFIKERKF EKKKLAMENK PKGNKIGGKK GSEGESKDAS NEEDSNSKNI 600
  601 LDGWQELPSL NIVNILYDLT PPEYIKKVIT EFGALPPSSV PVILREYKGS A

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..354] PSI-BLAST 4.39794 Heavy meromyosin subfragment
    2 View Details [355..538] ORFEUS 9.43 D-ribose-5-phosphate isomerase (RpiA), catalytic domain; D-ribose-5-phosphate isomerase (RpiA), lid domain
    3 View Details [539..651] MSA 1.074992 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • translation initiation factor activity
    		•  10.1099993541596 bayes_pls_golite062009
  • translation regulator activity
    		•  5.74669335554405 bayes_pls_golite062009
  • catalytic activity
    		•  1.31732715713197 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.30647139421574 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.09424756417577 bayes_pls_golite062009
  • binding
    		•  0.899200492696361 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.888163666064903 bayes_pls_golite062009
  • DNA binding
    		•  0.593071187541606 bayes_pls_golite062009
  • protein binding
    		•  0.0293610121675921 bayes_pls_golite062009
  • transcription factor activity
    		•  0.0259936471063739 bayes_pls_golite062009
    3 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.60

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle