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Protein Overview: DPOA2_YEAST

General Information:
Name(s) found: DPOA2_YEAST [Swiss-Prot]
Description(s) found:
  • DNA polymerase alpha subunit B OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=POL12 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 705 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSGSIDVITH FGPDADKPEI ITALENLTKL HALSVEDLYI KWEQFSNQRR QTHTDLTSKN  60
   61 IDEFKQFLQL QMEKRANQIS SSSKVNTSTK KPVIKKSLNS SPLFGLSIPK TPTLKKRKLH 120
  121 GPFSLSDSKQ TYNVGSEAET NEKGNSSLKL EFTPGMAEDA VGDSAPLSHA KSSDAKTPGS 180
  181 STFQTPTTNT PTTSRQNVPA GEILDSLNPE NIEISSGNPN VGLLSTEEPS YNQVKVEPFY 240
  241 DAKKYKFRTM RQNLQEASDV LDDQIESFTK IIQNHYKLSP NDFADPTIQS QSEIYAVGRI 300
  301 VPDSPTYDKF LNPESLSLET SRMGGVGRRV RLDLSQVNEL SFFLGQIVAF KGKNANGDYF 360
  361 TVNSILPLPY PNSPVSTSQE LQEFQANLEG SSLKVIVTCG PYFANDNFSL ELLQEFIDSI 420
  421 NNEVKPHVLI MFGPFIDITH PLIASGKLPN FPQFKTQPKT LDELFLKLFT PILKTISPHI 480
  481 QTVLIPSTKD AISNHAAYPQ ASLIRKALQL PKRNFKCMAN PSSFQINEIY FGCSNVDTFK 540
  541 DLKEVIKGGT TSSRYRLDRV SEHILQQRRY YPIFPGSIRT RIKPKDVSTK KETNDMESKE 600
  601 EKVYEHISGA DLDVSYLGLT EFVGGFSPDI MIIPSELQHF ARVVQNVVVI NPGRFIRATG 660
  661 NRGSYAQITV QCPDLEDGKL TLVEGEEPVY LHNVWKRARV DLIAS

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..198] deduced N/A No confident structure predictions are available.
    2 View Details [199..705] MSA 3.0129 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • hydrolase activity, acting on ester bonds
    		•  1.87325132707337 bayes_pls_golite062009
  • binding
    		•  1.30309680165893 bayes_pls_golite062009
  • catalytic activity
    		•  1.30037658165549 bayes_pls_golite062009
  • protein serine/threonine phosphatase activity
    		•  1.17916462117542 bayes_pls_golite062009
  • phosphoric ester hydrolase activity
    		•  0.950264524479969 bayes_pls_golite062009
  • phosphatase activity
    		•  0.829761417192212 bayes_pls_golite062009
  • phosphoprotein phosphatase activity
    		•  0.768201004870964 bayes_pls_golite062009
  • structural molecule activity
    		•  0.211411396269789 bayes_pls_golite062009
  • protein binding
    		•  0.20380491058914 bayes_pls_golite062009
  • hydrolase activity
    		•  0.070797330694107 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle