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Protein Overview: PNP_LISMO

General Information:
Name(s) found: PNP_LISMO [Swiss-Prot]
Description(s) found:
Found 6 descriptions.
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  • Polyribonucleotide nucleotidyltransferase OS=Listeria monocytogenes GN=pnp PE=3 SV=1 [Swiss-Prot]
    • Organism: Listeria monocytogenes
    Length: 723 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSEKQVFSTE WAGKTLSVEV GQLAKQASGA ALIRYGDTVV LTAAVGSKKP RPGDFFPLTV  60
   61 NYEEKMYSVG KVPGGFLKRE GRPSDRATLT ARLIDRPIRP LFAEGFRNEV QITSTVFSVD 120
  121 QDCSPEMAAM LGSSVALVIS DIPFEGPIAG VDVGRIDGKY VINPTIEQAE KSDISLTVAG 180
  181 TYDAINMVEA GAKEVSEEAM LEAIMFGHEE IKRLCEFQQQ IIAAVGKEKR EIELFVSDPE 240
  241 LEAEVKAASE GKMKTAIKTE EKKAREAAIE EVKEEILESY KAKELENESE ILSEVAHILE 300
  301 MIEKDEMRRL ISQDKIRPDG RKVNEIRPLS SEVGMLPRVH GSGLFTRGQT QALSVCTLAP 360
  361 LREHQIIDGL GTEEYKRFMH HYNFPQFSVG ETGPRRAPGR REIGHGALGE RALQYVIPSE 420
  421 EEFPYTIRLV SEVLESNGSS SQASICGSTL AMLDAGVPIK APVAGIAMGL VKLGDDYTIL 480
  481 SDIQGMEDHF GDMDFKVAGT KDGITALQMD IKIDGLSRQI LDEALTQAKE GRLHILEHLT 540
  541 STISAPREEL SAYAPKIITL NIKPEKIKDV IGPGGKQINA IIDETGVKID IEQDGTVYIA 600
  601 SQDQAMNRKA IAIIEDIVRE VEVGEVYTGK VRRIEKFGAF VELFKGTDGL VHISELAHER 660
  661 VGKVEDILKL GDEVTVKVIE VDQQGRVNLS RKALLEKKEQ PEGDKKPQAE KKFYPKTKKP 720
  721 ESK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..723] PSI-BLAST 140.0 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  3.95473097235349 bayes_pls_golite062009
  • exoribonuclease activity
    		•  3.2089851107515 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  3.18053249872858 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  2.16830676862423 bayes_pls_golite062009
  • RNA binding
    		•  2.05527376734941 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  2.04350689362549 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  2.04350689362549 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  2.04218282227834 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.90115575554186 bayes_pls_golite062009
  • structural molecule activity
    		•  1.69321127364043 bayes_pls_golite062009
    		• 1.2099360907571 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.20748032530392 bayes_pls_golite062009
  • hydrolase activity
    		•  1.18773479836745 bayes_pls_golite062009
  • mRNA binding
    		•  1.17402119891853 bayes_pls_golite062009
  • ligase activity
    		•  1.06979791212194 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.05662964529454 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • binding
    		•  0.907487229190259 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • DNA binding
    		•  0.828609700556836 bayes_pls_golite062009
  • nuclease activity
    		•  0.69721312877891 bayes_pls_golite062009
  • ATP-dependent peptidase activity
    		•  0.66778558090199 bayes_pls_golite062009
  • carbohydrate kinase activity
    		•  0.51810239718467 bayes_pls_golite062009
  • aspartate-tRNA ligase activity
    		•  0.504302440847948 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  0.477960254167 bayes_pls_golite062009
  • tRNA-specific ribonuclease activity
    		•  0.383567539949931 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.348601923227652 bayes_pls_golite062009
  • transcription factor activity
    		•  0.298729064067577 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.0740938021136293 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.0740938021136293 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.0287026367466632 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle