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Protein Overview: APN2_YEAST

General Information:
Name(s) found: APN2_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • DNA-(apurinic or apyrimidinic site) lyase 2 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=APN2 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 520 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSSENTLLD GKSENTIRFL TFNVNGIRTF FHYQPFSQMN QSLRSVFDFF RADIITFQEL  60
   61 KTEKLSISKW GRVDGFYSFI SIPQTRKGYS GVGCWIRIPE KNHPLYHALQ VVKAEEGITG 120
  121 YLTIKNGKHS AISYRNDVNQ GIGGYDSLDP DLDEKSALEL DSEGRCVMVE LACGIVIISV 180
  181 YCPANSNSSE EGEMFRLRFL KVLLRRVRNL DKIGKKIVLM GDVNVCRDLI DSADTLEQFS 240
  241 IPITDPMGGT KLEAQYRDKA IQFIINPDTP HRRIFNQILA DSLLPDASKR GILIDTTRLI 300
  301 QTRNRLKMYT VWNMLKNLRP SNYGSRIDFI LVSLKLERCI KAADILPDIL GSDHCPVYSD 360
  361 LDILDDRIEP GTTQVPIPKF EARYKYNLRN HNVLEMFAKK DTNKESNKQK YCVSKVMNTK 420
  421 KNSNIKNKSL DSFFQKVNGE KDDRIKESSE IPQQAKKRIS TPKLNFKDVF GKPPLCRHGE 480
  481 ESMLKTSKTS ANPGRKFWIC KRSRGDSNNT ESSCGFFQWV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..376] PSI-BLAST 154.0103 DNA repair endonuclease Hap1
    2 View Details [377..520] MSA 9.041989 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  1.43395324624057 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.848172443927544 bayes_pls_golite062009
  • DNA binding
    		•  0.675136468766578 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.649299186442773 bayes_pls_golite062009
  • protein binding
    		•  0.229377151617187 bayes_pls_golite062009
  • hydrolase activity
    		•  0.178972542898413 bayes_pls_golite062009
  • catalytic activity
    		•  0.0166038714828167 bayes_pls_golite062009
    2
    Term Confidence Notes
  • binding
    		•  1.43395324624057 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.848172443927544 bayes_pls_golite062009
  • DNA binding
    		•  0.675136468766578 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.649299186442773 bayes_pls_golite062009
  • protein binding
    		•  0.229377151617187 bayes_pls_golite062009
  • hydrolase activity
    		•  0.178972542898413 bayes_pls_golite062009
  • catalytic activity
    		•  0.0166038714828167 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.92

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle