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Protein Overview: RRP6_YEAST

General Information:
Name(s) found: RRP6_YEAST [Swiss-Prot]
Description(s) found:
Found 2 descriptions.
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  • Exosome complex exonuclease RRP6 OS=Saccharomyces cerevisiae (strain ATCC 204508 / S288c) GN=RRP6 PE=1 SV=1 [Swiss-Prot]
    • Organism: Saccharomyces cerevisiae S288c
    Length: 733 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MTSENPDVLL SRVINVVRAA SSLASQDVDF YKNLDRGFSK DLKSKADKLA DMANEIILSI  60
   61 DEHHESFELK EEDISDLWNN FGNIMDNLLE MSDHSLDKLN CAINSKSRGS DLQYLGEFSG 120
  121 KNFSPTKRVE KPQLKFKSPI DNSESHPFIP LLKEKPNALK PLSESLRLVD DDENNPSHYP 180
  181 HPYEYEIDHQ EYSPEILQIR EEIPSKSWDD SVPIWVDTST ELESMLEDLK NTKEIAVDLE 240
  241 HHDYRSYYGI VCLMQISTRE RDYLVDTLKL RENLHILNEV FTNPSIVKVF HGAFMDIIWL 300
  301 QRDLGLYVVG LFDTYHASKA IGLPRHSLAY LLENFANFKT SKKYQLADWR IRPLSKPMTA 360
  361 YARADTHFLL NIYDQLRNKL IESNKLAGVL YESRNVAKRR FEYSKYRPLT PSSEVYSPIE 420
  421 KESPWKILMY QYNIPPEREV LVRELYQWRD LIARRDDESP RFVMPNQLLA ALVAYTPTDV 480
  481 IGVVSLTNGV TEHVRQNAKL LANLIRDALR NIKNTNEEAT PIPSSETKAD GILLETISVP 540
  541 QIRDVMERFS VLCNSNISKS RAKPVTNSSI LLGKILPREE HDIAYSKDGL PNKVKTEDIR 600
  601 IRAQNFKSAL ANLEDIIFEI EKPLVVPVKL EEIKTVDPAS APNHSPEIDN LDDLVVLKKK 660
  661 NIQKKQPAKE KGVTEKDAVD YSKIPNILSN KPGQNNRQQK KRRFDPSSSD SNGPRAAKKR 720
  721 RPAAKGKNLS FKR

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..187] PSI-BLAST 8.69897 No description for 1j5fA_ was found.
    2 View Details [188..420] PSI-BLAST 1049.09691 No description for 1m0yA_ was found.
    3 View Details [421..527] MSA 11.125993 View MSA. Confident ab initio structure predictions are available.
    4 View Details [528..733] MSA 1.030973 View MSA. No confident structure predictions are available.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ribonuclease activity
    		•  8.897633904438 bayes_pls_golite062009
  • exoribonuclease activity
    		•  8.06617873723494 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  7.94412552409677 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  6.42138754551191 bayes_pls_golite062009
  • exonuclease activity
    		•  5.51415931494501 bayes_pls_golite062009
  • 3'-5' exonuclease activity
    		•  5.26222975375789 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  5.22368891565602 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  4.91798726616235 bayes_pls_golite062009
  • nuclease activity
    		•  3.11657409772275 bayes_pls_golite062009
  • ribonuclease H activity
    		•  2.91966688044755 bayes_pls_golite062009
  • hydrolase activity
    		•  2.78602644579272 bayes_pls_golite062009
    		• 2.73492915653996 bayes_pls_golite062009
  • endonuclease activity
    		•  2.63074055051349 bayes_pls_golite062009
  • endoribonuclease activity
    		•  2.59247838057313 bayes_pls_golite062009
  • binding
    		•  1.92623883978176 bayes_pls_golite062009
  • transcription regulator activity
    		•  1.7470402498426 bayes_pls_golite062009
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  1.74431545836806 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.73824903971928 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  1.59628511603826 bayes_pls_golite062009
  • DNA binding
    		•  1.46904214736532 bayes_pls_golite062009
  • RNA binding
    		•  1.43996903907704 bayes_pls_golite062009
  • catalytic activity
    		•  1.25233849524628 bayes_pls_golite062009
  • transcription factor activity
    		•  0.857419485352409 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.24906263529692 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.0189279348688405 bayes_pls_golite062009
  • 5'-3' exonuclease activity
    		•  0.00858768379909414 bayes_pls_golite062009
    2 No functions predicted.
    3 No functions predicted.
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.96

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle