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Protein Overview: EG12412

General Information:
Name(s) found: rfbB / EG12412 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • dTDP-glucose 4,6 dehydratase, NAD(P)-binding / TDP-glucose oxidoreductase-4,6 dehydratase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 361 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article]
    Biological Process: metabolic process [IEA]
    nucleotide-sugar metabolic process [IEA]
    lipopolysaccharide biosynthetic process [IEA]
    cellular metabolic process [IEA]
    Molecular Function: coenzyme binding [IEA]
    catalytic activity [IEA]
    dTDP-glucose 4,6-dehydratase activity [IEA]
    lyase activity [IEA]
    binding [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKILVTGGAG FIGSAVVRHI INNTQDSVVN VDKLTYAGNR ESLADVSDSE RYVFEHADIC  60
   61 DAPAMARIFA QHQPDAVMHL AAESHVDRSI TGPAAFIETN IVGTYVLLEA ARNYWSALDS 120
  121 DKKNSFRFHH ISTDEVYGDL PHPDEVNNTE ELPLFTETTA YAPSSPYSAS KASSDHLVRA 180
  181 WKRTYGLPTI VTNCSNNYGP YHFPEKLIPL VILNALEGKA LPIYGKGDQI RDWLYVEDHA 240
  241 RALYTVVTEG KAGETYNIGG HNEKKNIDVV LTICDLLDEI VPKEKSYREQ ITYVADRPGH 300
  301 DRRYAIDAEK IGRALGWKPQ ETFESGIRKT VEWYLSNTKW VDNVKSGAYQ SWIEQNYEGR 360
  361 Q

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..361] PSI-BLAST 109.0 dTDP-glucose 4,6-dehydratase (RmlB)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • UDP-glucose 4-epimerase activity
    		•  2.13934644118967 bayes_pls_golite062009
  • catalytic activity
    		•  1.79741889688267 bayes_pls_golite062009
  • oxidoreductase activity, acting on CH-OH group of donors
    		•  1.03956654822048 bayes_pls_golite062009
  • nucleic acid binding
    		•  0.868888700854563 bayes_pls_golite062009
  • oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
    		•  0.82673050487418 bayes_pls_golite062009
  • DNA binding
    		•  0.790382977752475 bayes_pls_golite062009
  • binding
    		•  0.784517759335365 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.613310508772122 bayes_pls_golite062009
  • transcription factor activity
    		•  0.11102650759187 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.69

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle