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Protein Overview: EG12938

General Information:
Name(s) found: rtcA / EG12938 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • RNA 3'-terminal phosphate cyclase / RNA 3'-terminal phosphate cyclase; 5' adenylyltransferase; physiological role unknown [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 338 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    nucleoplasm [IEA]
    Biological Process: RNA processing [IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    RNA-3'-phosphate cyclase activity [IEA]
    catalytic activity [IEA]
    ligase activity [IEA]
    ligase activity, forming phosphoric ester bonds [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKRMIALDGA QGEGGGQILR SALSLSMITG QPFTITSIRA GRAKPGLLRQ HLTAVKAATE  60
   61 ICGATVEGAE LGSQRLLFRP GTVRGGDYRF AIGSAGSCTL VLQTVLPALW FADGPSRVEV 120
  121 SGGTDNPSAP PADFIRRVLE PLLAKIGIHQ QTTLLRHGFY PAGGGVVATE VSPVASFNTL 180
  181 QLGERGNIVQ MRGEVLLAGV PRHVAEREIA TLAGSFSLHE QNIHNLPRDQ GPGNTVSLEV 240
  241 ESENITERFF VVGEKRVSAE VVAAQLVKEV KRYLASTAAV GEYLADQLVL PMALAGAGEF 300
  301 TVAHPSCHLL TNIAVVERFL PVRFSLIETD GVTRVSIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..338] PSI-BLAST 117.0 RNA 3'-terminal phosphate cyclase, RPTC, insert domain; RNA 3'-terminal phosphate cyclase, RPTC

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  2.54689525592227 bayes_pls_golite062009
  • transferase activity
    		•  1.7007536630883 bayes_pls_golite062009
  • transferase activity, transferring alkyl or aryl (other than methyl) groups
    		•  1.24131488513793 bayes_pls_golite062009
  • UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
    		•  0.249795968966795 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.46

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle