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Protein Overview: EG10651

General Information:
Name(s) found: nfo / EG10651 [EcoGene]
Description(s) found:
Found 5 descriptions.
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  • endonuclease IV with intrinsic 3'-5' exonuclease activity / AP endodeoxyribonuclease IV; member of soxRS regulon; endonuclease IV [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 285 amino acids

    Gene Ontology:
    Cellular Component: intracellular [IEA]
    Biological Process: DNA repair [IEA]
    response to DNA damage stimulus [IEA]
    Molecular Function: DNA binding [IEA]
    zinc ion binding [IEA]
    metal ion binding [IEA]
    endonuclease activity [IEA]
    nuclease activity [IEA]
    manganese ion binding [IEA]
    deoxyribonuclease IV (phage-T4-induced) activity [IEA]
    hydrolase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKYIGAHVSA AGGLANAAIR AAEIDATAFA LFTKNQRQWR AAPLTTQTID EFKAACEKYH  60
   61 YTSAQILPHD SYLINLGHPV TEALEKSRDA FIDEMQRCEQ LGLSLLNFHP GSHLMQISEE 120
  121 DCLARIAESI NIALDKTQGV TAVIENTAGQ GSNLGFKFEH LAAIIDGVED KSRVGVCIDT 180
  181 CHAFAAGYDL RTPAECEKTF ADFARTVGFK YLRGMHLNDA KSTFGSRVDR HHSLGEGNIG 240
  241 HDAFRWIMQD DRFDGIPLIL ETINPDIWAE EIAWLKAQQT EKAVA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..285] PSI-BLAST 71.045757 Endonuclease IV

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  1.66019571685402 bayes_pls_golite062009
  • deoxyribonuclease activity
    		•  0.97458966528485 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  0.36517654808269 bayes_pls_golite062009
  • endodeoxyribonuclease activity
    		•  0.19550406288989 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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