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Protein Overview: EG10363

General Information:
Name(s) found: galK / EG10363 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • galactokinase / Galactokinase [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 382 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDALink to PubMed article][IEA]
    Biological Process: galactose catabolic process via UDP-galactose [IMPLink to PubMed article]
    phosphorylation [IDALink to PubMed article][IEA]
    galactose metabolic process [IMPLink to PubMed articleLink to PubMed article]
    carbohydrate phosphorylation [IEA]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    kinase activity [IDA]
    galactokinase activity [IDALink to PubMed article][IEA][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSLKEKTQSL FANAFGYPAT HTIQAPGRVN LIGEHTDYND GFVLPCAIDY QTVISCAPRD  60
   61 DRKVRVMAAD YENQLDEFSL DAPIVAHENY QWANYVRGVV KHLQLRNNSF GGVDMVISGN 120
  121 VPQGAGLSSS ASLEVAVGTV LQQLYHLPLD GAQIALNGQE AENQFVGCNC GIMDQLISAL 180
  181 GKKDHALLID CRSLGTKAVS MPKGVAVVII NSNFKRTLVG SEYNTRREQC ETGARFFQQP 240
  241 ALRDVTIEEF NAVAHELDPI VAKRVRHILT ENARTVEAAS ALEQGDLKRM GELMAESHAS 300
  301 MRDDFEITVP QIDTLVEIVK AVIGDKGGVR MTGGGFGGCI VALIPEELVP AVQQAVAEQY 360
  361 EAKTGIKETF YVCKPSQGAG QC

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..382] PSI-BLAST 77.522879 crystal structure of human galactokinase complexed with MgAMPPNP and galactose

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • galactokinase activity
    		•  2.78881744973459 bayes_pls_golite062009
  • catalytic activity
    		•  0.878454819018611 bayes_pls_golite062009
  • hydrolase activity
    		•  0.740929677099368 bayes_pls_golite062009
  • nuclease activity
    		•  0.658641254758609 bayes_pls_golite062009
  • ribonuclease activity
    		•  0.545200648734771 bayes_pls_golite062009
  • binding
    		•  0.189327444560056 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.90

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle