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Protein Overview: EG10184

General Information:
Name(s) found: cysB / EG10184 [EcoGene]
Description(s) found:
Found 4 descriptions.
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  • N-acetylserine-responsive cysteine regulon transcriptional activator; autorepressor / Transcriptional activator for the Cys regulon; N-acetylserine induced; autorepressor [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 324 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IEA]
    Biological Process: transcription [IEA][IGILink to PubMed article]
    cysteine biosynthetic process [IEA]
    regulation of transcription, DNA-dependent [IEA]
    cellular amino acid biosynthetic process [IEA]
    Molecular Function: DNA binding [IEA]
    transcription factor activity [IEA]
    transcription activator activity [IGILink to PubMed article]
    transcription repressor activity [IDALink to PubMed article][IGILink to PubMed article][IMPLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKLQQLRYIV EVVNHNLNVS STAEGLYTSQ PGISKQVRML EDELGIQIFS RSGKHLTQVT  60
   61 PAGQEIIRIA REVLSKVDAI KSVAGEHTWP DKGSLYIATT HTQARYALPN VIKGFIERYP 120
  121 RVSLHMHQGS PTQIADAVSK GNADFAIATE ALHLYEDLVM LPCYHWNRAI VVTPDHPLAG 180
  181 KKAITIEELA QYPLVTYTFG FTGRSELDTA FNRAGLTPRI VFTATDADVI KTYVRLGLGV 240
  241 GVIASMAVDP VADPDLVRVD AHDIFSHSTT KIGFRRSTFL RSYMYDFIQR FAPHLTRDVV 300
  301 DAAVALRSNE EIEVMFKDIK LPEK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..324] PSI-BLAST 72.154902 COFACTOR BINDING FRAGMENT OF CYSB FROM KLEBSIELLA AEROGENES

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • transcription regulator activity
    		•  2.06846313752146 bayes_pls_golite062009
  • transcription factor activity
    		•  1.54776226622667 bayes_pls_golite062009
  • DNA binding
    		•  1.53867658911479 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.45471488657915 bayes_pls_golite062009
  • binding
    		•  1.29220115989941 bayes_pls_golite062009
  • catalytic activity
    		•  1.04475291968158 bayes_pls_golite062009
  • protein binding
    		•  0.0639574144110515 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle