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Protein Overview: EG10217

General Information:
Name(s) found: accD / EG10217 [EcoGene]
Description(s) found:
Found 6 descriptions.
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  • acetyl-CoA carboxylase, beta (carboxyltransferase) subunit / Acetyl-CoA carboxylase, carboxyltransferase beta subunit [EcoGene]
    • Organism: Escherichia coli str. K-12 substr. MG1655
    Length: 304 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    acetate CoA-transferase complex [IDALink to PubMed article]
    Biological Process: fatty acid biosynthetic process [IEA][IMPLink to PubMed article]
    negative regulation of translation [IDALink to PubMed article]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA]
    DNA binding [IMPLink to PubMed article]
    zinc ion binding [IDALink to PubMed articleLink to PubMed article][IEA]
    protein binding [IPILink to PubMed article]
    acetyl-CoA carboxylase activity [IEA]
    mRNA binding [IDALink to PubMed article]
    ligase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSWIERIKSN ITPTRKASIP EGVWTKCDSC GQVLYRAELE RNLEVCPKCD HHMRMTARNR  60
   61 LHSLLDEGSL VELGSELEPK DVLKFRDSKK YKDRLASAQK ETGEKDALVV MKGTLYGMPV 120
  121 VAAAFEFAFM GGSMGSVVGA RFVRAVEQAL EDNCPLICFS ASGGARMQEA LMSLMQMAKT 180
  181 SAALAKMQER GLPYISVLTD PTMGGVSASF AMLGDLNIAE PKALIGFAGP RVIEQTVREK 240
  241 LPPGFQRSEF LIEKGAIDMI VRRPEMRLKL ASILAKLMNL PAPNPEAPRE GVVVPPVPDQ 300
  301 EPEA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..304] PSI-BLAST 98.154902 No description for 2f9yB was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • acetyl-CoA carboxylase activity
    		•  10.6452464693016 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  10.4560118435089 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  10.291155621143 bayes_pls_golite062009
  • ligase activity
    		•  5.44906329604668 bayes_pls_golite062009
  • biotin carboxylase activity
    		•  4.73758144982083 bayes_pls_golite062009
  • enoyl-CoA hydratase activity
    		•  2.20341273353803 bayes_pls_golite062009
  • catalytic activity
    		•  1.46154163027498 bayes_pls_golite062009
  • 3-hydroxyacyl-CoA dehydrogenase activity
    		•  0.71437881404683 bayes_pls_golite062009
  • dodecenoyl-CoA delta-isomerase activity
    		•  0.712418056146834 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing C=C bonds
    		•  0.0918189681606029 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.58

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle