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Protein Overview: gi|51556273, gi|...

General Information:
Name(s) found: gi|51556273 [NCBI NR]
gi|50539393 [NCBI NR]
gi|149030965 [NCBI NR]
gi|109471071 [NCBI NR]
Description(s) found:
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  • gi|51556273|ref|NP_001003959.1| DNA methyltransferase 3B [Rattus norvegicus] [NCBI NR]
  • gi|50539393|tpe|CAE52319.1| TPA: putative DNA (cytosine-5) methyltransferase 3b [Rattus norvegicus] [NCBI NR]
  • gi|149030965|gb|EDL85992.1| rCG37517, isoform CRA_a [Rattus norvegicus] [NCBI NR]
  • gi|109471071|ref|XP_001061767.1| PREDICTED: similar to DNA methyltransferase 3B isoform 2 [Rattus norvegicus] [NCBI NR]
  • DNA methyltransferase 3B [Rattus norvegicus]gi|50539393|tpe|CAE52319.1| TPA: putative DNA (cytosine-5) methyltransferase 3b [Rattus norvegicus] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=10116 DNA methyltransferase 3B [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta]
  • Tax_Id=10116 DNA methyltransferase 3B [EBI-IPI_rat_3.05_04-04-2005_origrev.fasta]
  • DNA methyltransferase 3B [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • rCG37517, isoform CRA_a [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • TPA: putative DNA (cytosine-5) methyltransferase 3b [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • PREDICTED: similar to DNA methyltransferase 3B isoform 2 [Rattus norvegicus] [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta]
  • Tax_Id=10116 DNA METHYLTRANSFERASE 3B [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta]
  • Putative DNA (Cytosine-5) methyltransferase 3b OS=Rattus norvegicus GN=Dnmt3b [011711_HMR.fasta]
  • Protein Dnmt3b OS=Rattus norvegicus GN=Dnmt3b PE=2 SV=1 [20141208_RAT.fasta]
    • Organism: Rattus norvegicus
    Length: 859 amino acids

    Gene Ontology:
    Cellular Component: heterochromatin [UNKNOWN]
    nucleus [UNKNOWN][IDA]
    cytoplasm [UNKNOWN][IDA]
    intracellular membrane-bounded organelle [UNKNOWN]
    [NOT]nucleolus [UNKNOWN]
    nuclear heterochromatin [UNKNOWN][IEA]
    Biological Process: DNA methylation involved in embryonic development [UNKNOWN]
    positive regulation of neuron differentiation [IMP]
    S-adenosylmethioninamine metabolic process [IDA]
    methylation-dependent chromatin silencing [UNKNOWN][IEA]
    regulation of gene expression by genetic imprinting [UNKNOWN][IEA]
    protein complex localization [UNKNOWN][IEA]
    DNA methylation [UNKNOWN][IEA]
    S-adenosylhomocysteine metabolic process [IDA]
    negative regulation of histone H3-K9 methylation [UNKNOWN][IEA]
    positive regulation of gene expression [UNKNOWN][IEA]
    negative regulation of transcription [IMP]
    response to drug [IEP]
    positive regulation of histone H3-K4 methylation [UNKNOWN][IEA]
    DNA methylation on cytosine within a CG sequence [IDA]
    response to ionizing radiation [IEP]
    Molecular Function: DNA binding [IDA]
    DNA (cytosine-5-)-methyltransferase activity [UNKNOWN]
    zinc ion binding [IEA]
    protein binding [UNKNOWN][IPI]
    transcription corepressor activity [UNKNOWN][IEA]
    DNA (cytosine-5-)-methyltransferase activity, acting on CpG substrates [IDA]
    methyltransferase activity [IEA]
    unmethylated CpG binding [IDA]
    transferase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MKGDSRHLNE EEGASGYEDC IIVNGNCSDQ SSDTKDAPSP PVLEAICTEP VCTPETRGRR  60
   61 SSSRLSKREV SSLLNYTQDV VGDGDGEADD GDGSDILMMP KLTRETKDAR TPSESPAVRT 120
  121 RNSNSISSLE RQRTSPRITR GRQGRYHVQE YPVEFPATKS RRRRASSSAS TPWSSPASIE 180
  181 LMEDVTPKSS STPSVDLSQD GPQEGMDATQ VDAESRDGDS TEYQDDKEFG IGDLVWGKIK 240
  241 GFSWWPAMVV SWKATSKRQA MPGMRWVQWF GDGKFSEIAA DKLVALGLFS QHFNLATFNK 300
  301 LVSYRKAMYH TLEKAMVRAG KTFPSRPGDS LEDQLKPMLE WAHGGFKPTG IEGLKPNNKQ 360
  361 PEVHKSKVRR SGSRNLEARR RENKSRRRTT IDFAASEYST PPKRLKTNSY GGKDRGEDEE 420
  421 SRERMASDVT NNKGNLEDRC LSCGKKNPVS FHPLFEGGLC QSCRDRFLEL FYMYDEDGYQ 480
  481 SYCTVCCEGR ELLLCSNTSC CRCFCVECLE VLVGTGTAED AKLQEPWSCY MCLPQRCHGV 540
  541 LRRRKDWNMR LQDFFTTDPD LEEFEPPKLY PAIPAAKRRP IRVLSLFDGI ATGYLVLKDL 600
  601 GIKVEKYVAS EVCAESIAVG TIKHEGQIKY VNDVRKITKK NIEEWGPFDL VIGGSPCNDL 660
  661 SNVNPARKGL YEGTGRLFFE FYHLLNYTRP KEGDNRPFFW MFENVVAMKV NDKKDISRFL 720
  721 ACNPVMIDAI KVSAAHRARY FWGNLPGMNR PVIASKNDKL ELQDCLEFSR TAKLKKVQTI 780
  781 TTKSNSIRQG KNQLFPVVMN GKDDVLWCTE LERIFGFPAH YTDVSNMGRG ARQKLLGRSW 840
  841 SVPVIRHLFA PLKDYFACE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle