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Protein Overview: POLIB_ARATH

General Information:
Name(s) found: POLIB_ARATH [Swiss-Prot]
Description(s) found:
Found 13 descriptions.
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  • DNA polymerase I B, chloroplastic/mitochondrial OS=Arabidopsis thaliana GN=POLIB PE=2 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 1034 amino acids

    Gene Ontology:
    Cellular Component: nucleoid [IDA]
    chloroplast [IDA]
    mitochondrion [IDA]
    Biological Process: DNA replication [IEA][ISS]
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process [IEA]
    Molecular Function: nucleic acid binding [IEA]
    3'-5' exonuclease activity [IEA]
    DNA binding [IEA][ISS]
    DNA-directed DNA polymerase activity [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVSLRHLSP SSFWVSRRPR VSSSILSFLV PRRRILCTRK VAIIKGNAGY STATDCGGSH  60
   61 GFHHSGHQRS SSVEFSGEWK LNLGSKTARM VPPTVKQAGA VSAWREEVNN KLRGRNREYA 120
  121 NNQDDAFGNG SYILKGFVPK IDDVHSYGNG QNFDYNLKPG TDITTLGREL NGFMQTNSIR 180
  181 GSVVALPSKD IEVGETTDVT LKPLNSDTTL DNASYKKTAT ISKVEKCTNL SQVRANLKKI 240
  241 YNRVRVVDNV SSAKETVALL MNQYRNLVHA CDTEVSRIDV KTETPVDHGE MICFSIYCGS 300
  301 EADFGDGKSC IWVDVLGENG RDILAEFKPF FEDSSIKKVW HNYSFDNHII RNYGIKLSGF 360
  361 HGDTMHMARL WDSSRRISGG YSLEALTSDP KVLGGTETKE EAELFGKISM KKIFGKGKLK 420
  421 KDGSEGKLVI IPPVKELQME DREAWISYSA LDSISTLKLY ESMKKQLQAK KWFLDGKLIS 480
  481 KKNMFDFYQE YWQPFGELLA KMESEGMLVD RDYLAQIEIV AKAEQEIAVS RFRNWASKHC 540
  541 PDAKHMNVGS DTQLRQLFFG GISNSCNDED LPYEKLFKVP NVDKVIEEGK KRATKFRNIK 600
  601 LHRISDRPLP TEKFTASGWP SVSGDTLKAL AGKVSAEYDY MEGVLDTCLE ENIGDDDCIS 660
  661 LPDEVVETQH VNTSVESDTS AYGTAFDAFG GGESGKEACH AIAALCEVCS IDSLISNFIL 720
  721 PLQGSNVSGK DGRVHCSLNI NTETGRLSAR RPNLQNQPAL EKDRYKIRQA FIASPGNSLI 780
  781 VADYGQLELR ILAHLASCES MKEAFIAGGD FHSRTAMNMY PHIREAVENG EVLLEWHPQP 840
  841 GQEKPPVPLL KDAFASERRK AKMLNFSIAY GKTAIGLSRD WKVSREEAQD TVNLWYNDRQ 900
  901 EVRKWQELRK KEAIQKGYVL TLLGRARKFP EYRSRAQKNH IERAAINTPV QGSAADVAMC 960
  961 AMLEISNNQR LKELGWKLLL QVHDEVILEG PSESAENAKD IVVNCMSEPF NGKNILSVDL1020
 1021 SVDAKCAQNW YAGK

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..183] PSI-BLAST 21.0 T5 5'-exonuclease
    2 View Details [184..303] PSI-BLAST 11.045757 No description for 2hbjA was found.
    3 View Details [304..1034] PSI-BLAST 139.0 5' to 3' exonuclease domain of DNA polymerase Taq; Exonuclease domain of prokaryotic DNA polymerase; DNA polymerase I (Klenow fragment)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • catalytic activity
    		•  0.845290320008287 bayes_pls_golite062009
  • hydrolase activity
    		•  0.31554871338907 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.12799711467808 bayes_pls_golite062009
  • nuclease activity
    		•  0.0878151841480506 bayes_pls_golite062009
    2 No functions predicted.
    3
    Term Confidence Notes
  • catalytic activity
    		•  0.518931870161593 bayes_pls_golite062009
  • transferase activity
    		•  0.35636561630516 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.32441153240842 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.29860211454192 bayes_pls_golite062009
  • DNA polymerase activity
    		•  0.0603497936698201 bayes_pls_golite062009
  • DNA-directed DNA polymerase activity
    		•  0.0602875211585996 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.49

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle