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Protein Overview: XRN4_ARATH

General Information:
Name(s) found: XRN4_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|75262833|sp|Q9FQ04.1|XRN4_ARATH RecName: Full=5'-3' exoribonuclease 4; AltName: Full=Protein EXORIBONUCLEASE 4; AltName: Full=Protein ACC INSENSITIVE 1; AltName: Full=Protein ETHYLENE INSENSITIVE 5 [NCBI NR]
  • gi|20259665|gb|AAM14350.1| putative exonuclease [Arabidopsis thaliana] [NCBI NR]
  • gi|17381112|gb|AAL36368.1| putative exonuclease [Arabidopsis thaliana] [NCBI NR]
  • gi|15221841|ref|NP_175851.1| XRN4 (EXORIBONUCLEASE 4); 5'-3' exonuclease/ 5'-3' exoribonuclease/ nucleic acid binding [Arabidopsis thaliana] [NCBI NR]
  • gi|11875626|gb|AAG40731.1|AF286718_1 XRN4 [Arabidopsis thaliana] [NCBI NR]
  • gi|109627646|gb|ABG34298.1| At1g54490 [Arabidopsis thaliana] [NCBI NR]
  • 5'-3' exoribonuclease 4 OS=Arabidopsis thaliana GN=XRN4 PE=2 SV=1 [Swiss-Prot]
  • putative exonuclease [Arabidopsis thaliana]gi|17381112|gb|AAL36368.1| putative exonuclease [Arabidopsis thaliana]gi|11875626|gb|AAG40731.1| XRN4 [Arabidopsis thaliana]gi|15221841|ref|NP_175851.1| 5'-3' exoribonuclease (XRN4) [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 5'-3' exoribonuclease (XRN4) [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: EIN5, XRN4, AIN1 | AIN1 (ACC INSENSITIVE 1); 5'-3' exonuclease/ nucleic acid binding | chr1:20353967-20360317 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • putative exonuclease [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • At1g54490 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • XRN4; 5'-3' exonuclease/ exonuclease/ nucleic acid binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • XRN4 [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: AIN1, EIN5, XRN4, ATXRN4 | exoribonuclease 4 | chr1:20350300-20356650 FORWARD LENGTH=947 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
    • Organism: Arabidopsis thaliana
    Length: 947 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    Biological Process: unidimensional cell growth [IMP]
    deadenylation-independent decapping of nuclear-transcribed mRNA [IMP]
    nuclear-transcribed mRNA catabolic process, exonucleolytic [IMP]
    ethylene mediated signaling pathway [IGI][IMP]
    response to 1-aminocyclopropane-1-carboxylic acid [IMP]
    gravitropism [IMP]
    response to ethylene stimulus [IMP]
    regulation of gene expression, epigenetic [IMP]
    miRNA catabolic process [IMP]
    Molecular Function: 5'-3' exonuclease activity [ISS]
    nucleic acid binding [ISS]
    5'-3' exoribonuclease activity [IGI][IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGVPAFYRWL ADRYPKSISD VVEEEPTDGG RGDLIPVDIT RPNPNGFEFD NLYLDMNGII  60
   61 HPCFHPEGKP APATYDDVFK SMFEYIDHLF TLVRPRKILY LAIDGVAPRA KMNQQRSRRF 120
  121 RAAKDAAEAE AEEERLRKDF EMEGQILSAK EKAETCDSNV ITPGTPFMAI LSVALQYYIQ 180
  181 SRLNHNPGWR YVKVILSDSN VPGEGEHKIM SYIRLQRNLP GFDPNTRHCL YGLDADLIML 240
  241 SLATHEVHFS ILREVITYPG QQEKCFVCGQ TGHFASDCPG KSGSNNAAAD IPIHKKKYQF 300
  301 LNIWVLREYL QYELAIPDPP FMINFERIID DFVFLCFFVG NDFLPHMPTL EIREGAINLL 360
  361 MHVYRKEFTA MGGYLTDSGE VLLDRVEHFI QAVAVNEDKI FQKRTRIKQS MDNNEEMKQR 420
  421 SRRDPSEVPP EPIDDKIKLG EPGYKERYYA EKFSTTNPEE TEQIKQDMVL KYVEGLCWVC 480
  481 RYYYQGVCSW QWFYPYHYAP FASDLKNLPD LEITFFIGEP FKPFDQLMGT LPAASSNALP 540
  541 GEYRKLMTDP SSPILKFYPA DFELDMNGKR FAWQGIAKLP FIEEKLLLAA TRKLEETLTV 600
  601 EEQQRNSVML DLLYVHPAHP LGQRILQYYH FYQHMPPHEC LPWMIDPNSS QGMNGFLWFS 660
  661 ERNGFQTRVD SPVNGLPCIE QNRALNVTYL CPAKHSHISE PPRGAIIPDK ILTSVDIKPF 720
  721 PPLWHEDNSN RRRQARDRPQ VVGAIAGPSL GEAAHRLIKN TLNMKSSTGA ASGLIDPNGY 780
  781 YRNVPGNYSY GGVNRPRAPG PSPYRKAYDD DSSYYYGKYN NSTQGTFNNG PRYPYPSNGS 840
  841 QDYNRNYNSK IVAEQHNRGG LGAGMSGLSI EDNGRSKQLY SSYTEAANAN LNPLPSPPTQ 900
  901 WIGTQPGGNF VGGYYRDGVG YSETNGKSVK KVIYQAKTQP SHRGANL

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..150] MSA 3.101966 View MSA. No confident structure predictions are available.
    2 View Details [151..281] deduced N/A No confident structure predictions are available.
    3 View Details [282..498] deduced N/A No confident structure predictions are available.
    4 View Details [499..597] deduced N/A No confident structure predictions are available.
    5 View Details [598..947] PSI-BLAST 22.221849 No description for 1y0fB was found.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle