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Protein Overview: gi|3281907, gi|7...

General Information:
Name(s) found: gi|7512045 [NCBI NR]
gi|3281907 [NCBI NR]
Description(s) found:
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  • pir||T13751 transcription factor sin3 - fruit fly (Drosophila melanogaster) [NCBI NR]
  • gi|3281907|emb|CAA07550.1| transcription factor [Drosophila melanogaster] [NCBI NR]
  • transcription factor [Drosophila melanogaster]gi|7512045|pir||T13751 transcription factor sin3 - fruit fly (Drosophila melanogaster) [nrdb_11152004_Chlamydomonas]
  • transcription factor [Drosophila melanogaster] [nr-271106-contam.fasta]
  • Transcription factor OS=Drosophila melanogaster GN=Sin3A PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta]
    • Organism: Drosophila melanogaster
    Length: 2061 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA][ISS][NAS]
    euchromatin [TAS]
    cytoplasm [IDA]
    Sin3 complex [NAS]
    chromatin [IDA]
    Biological Process: muscle organ development [IMP]
    negative regulation of transcription, DNA-dependent [IMP][TAS]
    negative regulation of transcription [IEP]
    peripheral nervous system development [TAS]
    regulation of transcription, DNA-dependent [IEA]
    neuron development [IMP]
    regulation of transcription [ISS]
    regulation of mitotic cell cycle [IMP]
    dendrite morphogenesis [IMP]
    Molecular Function: transcription factor activity [ISS]
    transcription cofactor activity [NAS]
    RNA polymerase II transcription factor activity [NAS]
    transcription repressor activity [IDA][IMP]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MMKRTRVDEV QFGTRPVPQT SGGVGVGVVG VTGGGPTSGG GGTATVGVNT TGVTIGTVVP  60
   61 SAHNATISGI GSIHHRILTP QHGGAQTIAY LPSTTPTATN LKTTSSIVDS TTAGGPVGAG 120
  121 AQVAVGVGSA AGGGGVVVST GSTGTQTLQY TTSYSVASIQ AGGTLKANTA DGANTVQIHV 180
  181 TGGGAANNPA SAQTVSSSSQ TGTIRQRTIS GTQTVATAVG NLATISQQQP VQQSPLGKAQ 240
  241 TPPSSVVANS IPVGGTTPPQ GQSGNATPRL KVEDALSYLD QVKYQYADQP QIYNNFLDIM 300
  301 KEFKSHCIDT PGVIERVSTL FKGHTELIYG FNMFLPPGYK IEIHSDALGC SVPVVSMPSP 360
  361 PGAPTSTGTV HMLTGNSSMS GAGHIAIKTT NAATLTPAAG AGAAAAAAAV AQIQSAGAVN 420
  421 LMTHGGASLT QTTIHALQQA TPPQSQSPGG GHVHVSVTNS TAANAVVPGQ PGISVSAHNV 480
  481 PQNYSRDRER ATITPTGQVA GAAANVNASA SIVVGGPPTP NSLSELSPHG GAGGGPGAGA 540
  541 AQHNLHHIQQ AHQSILLGET GQQNQPVEFN HAITYVNKIK NRFQNQPAKY KKFLEILHDY 600
  601 QREQKVMKEG SLNQGKMLTE QEVYTQVAKL FGQDEDLLRE FGQFLPDATN HQSGQYMSKS 660
  661 ASVHNDHGKR PTATLSGGAH ITMSSASPAP SGSPLHLGAT TLPQIDKSAH AAAIGNLSAV 720
  721 NTSVSIKTYN NNQQQQNHVI GSGLNATRND ILFEKDYHAG LQQQAHQRGA GVGGHHHLAG 780
  781 TAAGANIGRP GVGASVMVSY DKEHRNNHHV QKYVGHAPNQ NLTHGHNAKK SPSYGIPSVI 840
  841 GSMPHISDNS LDRSSPGISY ATPPLPSGPH GQHNSGSATR RPGDDSLVGH YASGAPPAKR 900
  901 PKPYCRDVSF SEASSKCTIS DAAFFDKVRK ALRSPEVYDN FLRCLTLFNQ EIVSKTELLG 960
  961 LASPFLMKFP DLLRWLTDFL GPPSGQPAGG LIDGMPLAAT QRQGGGSSNS SHDRGTSHQS1020
 1021 AAEYVQDVDL SSCKRLGASY CALPQSTVPK KCSGRTALCR EVLNDKWVSF PTWASEDSTF1080
 1081 VTSRKTQFEE TIYRTEDERF ELDLVIEVNS ATIRVLENLQ KKMSRMSTEE LSKFHLDDHL1140
 1141 GGTSQTIHQR AIHRIYGDKS GEIITGMKKN PFVAVPIVLK RLKVKEEEWR EAQKTFNKQW1200
 1201 REQNEKYYLK SLDHQAINFK PNDMKALRSK SLFNEIETLY DERHDQEDDA MEPFGPHLVL1260
 1261 PYKDKTILDD AANLLIHHVK RQTGIQKQEK QKIKQIIRQF VPDLFFAPRQ PLSDDERDDA1320
 1321 FPFLVDDNTK MDVDSPLGRT ESSTRNAKST PSESASPARS NASTSSVTPA GIKKETDDSK1380
 1381 ATTGSFAPAS SATASSATPV DDATPSTSSA AAAASAASSS TVSGTEGKPK DDPLSSHKEE1440
 1441 GAGSTSSGVA TSPRQAQDTA GAGVDVEIKL EHPADFSNPK LLPPHAHGQR EDESYTLFFA1500
 1501 NNNWYLFLRL HAILCDRLHV MYERARLLAI EEERCRVNRR ESTATALRLK PKPEIQVEDY1560
 1561 YPTFLDMLKN VLDGNMDSNT FEDTMREMFG IYAYISFTLD KVVSNAVRQL QYCVTERAAL1620
 1621 DCVELFATEQ RRGCTGGFCR DAHKTFDREM SYQRKAESIL NEENCFKVYI YKIDCRVTIE1680
 1681 LLDSEPEEVD KPAALKAQKF SKYVERLANP ALGGGGNTGR SDSALGNDSV VDGSDIKTEA1740
 1741 NEDTAELRYR EGGIGGAGKA RFLVRNKRRS KLLEEQVRQL FEHRRNRIEQ HGTAASLESI1800
 1801 SVDSAISSNS TTGGGGSGSN NNNNNNNNNS WGGKRLERLG APQVGLAEQY AFNDRDEIST1860
 1861 NISNGRCFVT SKNLKLLKYD AVRRAKKSHC RVTQAKYAHF QTYVNKWLQQ HVSEQQQQNC1920
 1921 VDWLLGKTAD QINASGWGSA SKTKTVQQKD TSKTPYRIYN RYRVVQSAVS GGLMSATAPT1980
 1981 PDGSVPAVNS APSGSVSTVN NVQGSAAVSS TSHSMCNSSI LSADSTTNTN ASAQQQQHCN2040
 2041 SAAAATTPNA EALQQVRPME S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data



    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.44

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle