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Protein Overview: gi|48425314, gi|...

General Information:
Name(s) found: gi|7546607 [NCBI NR]
gi|48425315 [NCBI NR]
gi|48425314 [NCBI NR]
gi|146387504 [NCBI NR]
gi|146387503 [NCBI NR]
gi|109157936 [NCBI NR]
gi|109157933 [NCBI NR]
Description(s) found:
Found 16 descriptions.
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  • gi|7546607|pdb|3BMP|A Chain A, Human Bone Morphogenetic Protein-2 (Bmp-2) [NCBI NR]
  • gi|48425315|pdb|1REW|B Chain B, Structural Refinement Of The Complex Of Bone Morphogenetic Protein 2 And Its Type Ia Receptor [NCBI NR]
  • gi|48425314|pdb|1REW|A Chain A, Structural Refinement Of The Complex Of Bone Morphogenetic Protein 2 And Its Type Ia Receptor [NCBI NR]
  • gi|146387504|pdb|2H62|B Chain B, Crystal Structure Of A Ternary Ligand-Receptor Complex Of Bmp-2 [NCBI NR]
  • gi|146387503|pdb|2H62|A Chain A, Crystal Structure Of A Ternary Ligand-Receptor Complex Of Bmp-2 [NCBI NR]
  • gi|109157936|pdb|2GOO|D Chain D, Ternary Complex Of Bmp-2 Bound To Bmpr-Ia-Ecd And Actrii-Ecd [NCBI NR]
  • gi|109157933|pdb|2GOO|A Chain A, Ternary Complex Of Bmp-2 Bound To Bmpr-Ia-Ecd And Actrii-Ecd [NCBI NR]
    • Organism: Homo sapiens
    Length: 114 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QAKHKQRKRL KSSCKRHPLY VDFSDVGWND WIVAPPGYHA FYCHGECPFP LADHLNSTNH  60
   61 AIVQTLVNSV NSKIPKACCV PTELSAISML YLDENEKVVL KNYQDMVVEG CGCR

    Protein Complex Data

      PUBLICATION TOPOLOGY COCOMPLEXED PROTEINS
    View Details Noble WS, et al. (2009) Manuscript in preparation. gi|112491310 gi|48425314, gi|...

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..114] PSI-BLAST 40.69897 Bone morphogenetic protein-2 (BMP-2)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • receptor binding
    		•  4.70889547404918 bayes_pls_golite062009
  • growth factor activity
    		•  3.55277889903829 bayes_pls_golite062009
  • protein binding
    		•  3.16282476674164 bayes_pls_golite062009
  • cytokine activity
    		•  2.99020989034786 bayes_pls_golite062009
  • binding
    		•  2.37954321554411 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
    		•  2.16322447608029 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
    		•  2.00657419237426 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
    		•  2.00657419237426 bayes_pls_golite062009
  • cell surface binding
    		•  1.99110766256982 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 1 binding
    		•  1.87722086999547 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
    		•  1.74489645820593 bayes_pls_golite062009
  • glycosaminoglycan binding
    		•  1.67879530820663 bayes_pls_golite062009
  • protein dimerization activity
    		•  1.44846386076063 bayes_pls_golite062009
  • vascular endothelial growth factor receptor 2 binding
    		•  1.44790236067538 bayes_pls_golite062009
  • hormone activity
    		•  1.39628583804208 bayes_pls_golite062009
  • heparin binding
    		•  1.30997160523692 bayes_pls_golite062009
  • growth factor binding
    		•  1.28535209856904 bayes_pls_golite062009
  • vascular endothelial growth factor receptor binding
    		•  1.1973768181124 bayes_pls_golite062009
  • glial cell line-derived neurotrophic factor receptor binding
    		•  1.16821412683065 bayes_pls_golite062009
  • polysaccharide binding
    		•  1.16191864095271 bayes_pls_golite062009
  • protein homodimerization activity
    		•  1.13743310822539 bayes_pls_golite062009
  • platelet-derived growth factor receptor binding
    		•  1.12951786832285 bayes_pls_golite062009
  • pattern binding
    		•  1.03800950458236 bayes_pls_golite062009
  • identical protein binding
    		•  1.0030262164995 bayes_pls_golite062009
  • neurotrophin receptor binding
    		•  0.81172494974121 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.408562885230686 bayes_pls_golite062009
  • platelet-derived growth factor binding
    		•  0.31124485646439 bayes_pls_golite062009
  • fibronectin binding
    		•  0.1110090445978 bayes_pls_golite062009
  • collagen binding
    		•  0.0532357400924206 bayes_pls_golite062009
  • carbohydrate binding
    		•  0.0235054088545197 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle