Protein Overview: ABCC8_RAT

General Information:
Name(s) found:	ABCC8_RAT [Swiss-Prot]
Description(s) found: Found 11 descriptions. SHOW ALL	ATP-binding cassette sub-family C member 8 OS=Rattus norvegicus GN=Abcc8 PE=1 SV=4 [Swiss-Prot]
Organism:	Rattus norvegicus
Length:	1582 amino acids
Gene Ontology:
Cellular Component:	ATP-sensitive potassium channel complex [IMP][TAS] sarcolemma [IDA] membrane [IEA] integral to membrane [IEA] synaptic vesicle membrane [IMP] plasma membrane [UNKNOWN]
Biological Process:	response to zinc ion [IDA] response to insulin stimulus [IEP] transmembrane transport [IEA] response to drug [IEP] response to chemical stimulus [IDA] response to pH [IDA] response to lipopolysaccharide [IEP] positive regulation of potassium ion transport [IDA] negative regulation of insulin secretion [IDA]
Molecular Function:	nucleotide binding [IEA] ATPase activity [IEA] ATP binding [IMP] sulfonylurea receptor activity [TAS] ATPase activity, coupled to transmembrane movement of substances [IEA] syntaxin binding [IPI] receptor activity [IEA] potassium channel activity [IMP]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MPLAFCGTEN HSAAYRVDQG VLNNGCFVDA LNVVPHVFLL FITFPILFIG WGSQSSKVHI  60
   61 HHSTWLHFPG HNLRWILTFI LLFVLVCEIA EGILSDGVTE SRHLHLYMPA GMAFMAAITS 120
  121 VVYYHNIETS NFPKLLIALL IYWTLAFITK TIKFVKFYDH AIGFSQLRFC LTGLLVILYG 180
  181 MLLLVEVNVI RVRRYVFFKT PREVKPPEDL QDLGVRFLQP FVNLLSKGTY WWMNAFIKTA 240
  241 HKKPIDLRAI GKLPIAMRAL TNYQRLCLAF DAQARKDTQS QQGARAIWRA LCHAFGRRLV 300
  301 LSSTFRILAD LLGFAGPLCI FGIVDHLGKE NHVFQPKTQF LGVYFVSSQE FLGNAYVLAV 360
  361 LLFLALLLQR TFLQASYYVA IETGINLRGA IQTKIYNKIM HLSTSNLSMG EMTAGQICNL 420
  421 VAIDTNQLMW FFFLCPNLWA MPVQIIVGVI LLYYILGVSA LIGAAVIILL APVQYFVATK 480
  481 LSQAQRSTLE YSNERLKQTN EMLRGIKLLK LYAWENIFCS RVEKTRRKEM TSLRAFAVYT 540
  541 SISIFMNTAI PIAAVLITFV GHVSFFKESD FSPSVAFASL SLFHILVTPL FLLSSVVRST 600
  601 VKALVSVQKL SEFLSSAEIR EEQCAPREPA PQGQAGKYQA VPLKVVNRKR PAREEVRDLL 660
  661 GPLQRLTPST DGDADNFCVQ IIGGFFTWTP DGIPTLSNIT IRIPRGQLTM IVGQVGCGKS 720
  721 SLLLATLGEM QKVSGAVFWN SSLPDSEGED PSNPERETAA DSDARSRGPV AYASQKPWLL 780
  781 NATVEENITF ESPFNKQRYK MVIEACSLQP DIDILPHGDQ TQIGERGINL SGGQRQRISV 840
  841 ARALYQHTNV VFLDDPFSAL DVHLSDHLMQ AGILELLRDD KRTVVLVTHK LQYLPHADWI 900
  901 IAMKDGTIQR EGTLKDFQRS ECQLFEHWKT LMNRQDQELE KETVMERKAP EPSQGLPRAM 960
  961 SSRDGLLLDE DEEEEEAAES EEDDNLSSVL HQRAKIPWRA CTKYLSSAGI LLLSLLVFSQ1020
 1021 LLKHMVLVAI DYWLAKWTDS ALVLSPAARN CSLSQECALD QSVYAMVFTV LCSLGIALCL1080
 1081 VTSVTVEWTG LKVAKRLHRS LLNRIILAPM RFFETTPLGS ILNRFSSDCN TIDQHIPSTL1140
 1141 ECLSRSTLLC VSALAVISYV TPVFLVALLP LAVVCYFIQK YFRVASRDLQ QLDDTTQLPL1200
 1201 LSHFAETVEG LTTIRAFRYE ARFQQKLLEY TDSNNIASLF LTAANRWLEV RMEYIGACVV1260
 1261 LIAAATSISN SLHRELSAGL VGLGLTYALM VSNYLNWMVR NLADMEIQLG AVKRIHTLLK1320
 1321 TEAESYEGLL APSLIPKNWP DQGKIQIQNL SVRYDSSLKP VLKHVNALIS PGQKIGICGR1380
 1381 TGSGKSSFSL AFFRMVDMFE GRIIIDGIDI AKLPLHTLRS RLSIILQDPV LFSGTIRFNL1440
 1441 DPEKKCSDST LWEALEIAQL KLVVKALPGG LDAIITEGGE NFSQGQRQLF CLARAFVRKT1500
 1501 SIFIMDEATA SIDMATENIL QKVVMTAFAD RTVVTIAHRV HTILSADLVM VLKRGAILEF1560
 1561 DKPEKLLSQK DSVFASFVRA DK

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

NOT SHOWING SINGLE HITS. [ Show Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein Overview: ABCC8_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: