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Protein Overview: CG17471-PB, CG17...

General Information:
Name(s) found: CG17471-PB / FBpp0099993 [FlyBase]
CG17471-PA / FBpp0099992 [FlyBase]
Description(s) found:
Found 29 descriptions.
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  • This gene is referred to in FlyBase by the symbol Dmel\CG17471 (CG17471, FBgn0039924). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1213042..1217466. It has the cytological map location 102F8. Based on sequence similarity, it is predicted to have molecular function</span>: 1-phosphatidylinositol-4-phosphate 5-kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; cell adhesion; actin filament organization. No alleles are reported. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
  • This gene is referred to in FlyBase by the symbol Dmel\CG17471 (CG17471, FBgn0039924). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 4:1213042..1217466. It has the cytological map location 102F8. Based on sequence similarity, it is predicted to have molecular function</span>: 1-phosphatidylinositol-4-phosphate 5-kinase activity. There is experimental evidence that it is involved in the biological process</span>: regulation of cell shape; cell adhesion; actin filament organization. No alleles are reported. It has 2 annotated transcripts and 2 annotated polypeptides. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 404 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: regulation of cell shape [IMP]
    actin filament organization [IMP]
    cell adhesion [IMP]
    phosphatidylinositol metabolic process [IEA]
    phosphorylation [NAS]
    Molecular Function: 1-phosphatidylinositol-4-phosphate 5-kinase activity [ISS][NAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEKKISSSSQ PRILKKKHFR VKHQKVKLFR ANEPILSVFM WGINHTINEL SHVNIPVMLL  60
   61 PDDFRAYSKI KVDNHLFNKE NMPSHFKVKE YCPLVFRNLR ERFGVDDVDY RESLTRSQPI 120
  121 QIDSSGKSGA QFYQSYDKFF IIKSLTSEEI ERMHAFLKQY HPYVVERHGK TLLPQYLGMY 180
  181 RITVESVQYY FVVMRNVFSS HLTIHKKFDL KGSTVDREAS EKELEKNLPT FKDNDFIKQK 240
  241 VKLDIGKEAK DKLMDTLSND VDLLTKLHIM DYSLLVGVHD CVRAEEEALQ GDNILTVGRS 300
  301 ENSESEECDS GERWTYNTPP DSPRGAQYKE VVYEVDIYDI PSIEEKREIY FIAIIDVLTQ 360
  361 YGVKKQAAKA AKTVKYGSNV DGISTCDPEQ YAKRFLDFMD KAIE

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..404] PSI-BLAST 113.0 Phosphatidylinositol phosphate kinase IIbeta, PIPK IIbeta

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • inositol or phosphatidylinositol kinase activity
    		•  4.31726963575315 bayes_pls_golite062009
  • lipid kinase activity
    		•  3.63026201392483 bayes_pls_golite062009
  • phosphatidylinositol phosphate kinase activity
    		•  3.29315211323714 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
    		•  2.8512866333787 bayes_pls_golite062009
  • kinase activity
    		•  2.68971389233526 bayes_pls_golite062009
  • 1-phosphatidylinositol-4-phosphate 5-kinase activity
    		•  2.65186975336776 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  2.31077377326314 bayes_pls_golite062009
  • catalytic activity
    		•  1.87792712964225 bayes_pls_golite062009
  • binding
    		•  1.23659721062619 bayes_pls_golite062009
  • transferase activity
    		•  1.20817067352467 bayes_pls_golite062009
  • signal transducer activity
    		•  0.544033754158941 bayes_pls_golite062009
  • molecular transducer activity
    		•  0.544033754158941 bayes_pls_golite062009
  • ligase activity
    		•  0.435608917599349 bayes_pls_golite062009
  • protein kinase activity
    		•  0.422676745032915 bayes_pls_golite062009
  • protein binding
    		•  0.382966234080422 bayes_pls_golite062009
  • protein serine/threonine kinase activity
    		•  0.189737258618863 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.14608192065514 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle