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Protein Overview: gi|190408465

General Information:
Name(s) found: gi|190408465 [NCBI NR]
Description(s) found:
  • gi|190408465|gb|EDV11730.1| ribonuclease III [Saccharomyces cerevisiae RM11-1a] [NCBI NR]
    • Organism: Saccharomyces cerevisiae RM11-1a
    Length: 471 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGSKVAGKKK TQNDNKLDNE NGSQQRENIN TKTLLKGNLK ISNYKYLEVI QLEHAVTKLV  60
   61 ESYNKIIELS PNLVAYNEAV NNQDRVPVQI LPSLSRYQLK LAAELKTLHD LKKDAILTEI 120
  121 TDYENEFDTE QKQPILQEIS KADMEKLEKL EQVKREKREK IDVNVYENLN EKEDEEEDEG 180
  181 EDSYDPTKAG DIVKATKWPP KLPEIQDLAI RARVFIHKST IKDKVYLSGS EMINAHNERL 240
  241 EFLGDSILNS VMTLIIYNKF PDYSEGQLST LRMNLVSNEQ IKQWSIMYNF HEKLKTNFDL 300
  301 KDENSNFQNG KLKLYADVFE AYIGGLMEDD PRNNLPKIRK WLRKLAKPVI EEATRNQVAL 360
  361 EKTDKLDMNA KRQLYSLIGY ASLRLHYVTV KKPTAVDPNS IVECRVGDGT VLGTGVGRNI 420
  421 KIAGIRAAEN ALRDKKMLDF YAKQRAAIPR SESVLKDPSQ KNKKRKFSDT S

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..112] MSA 1.00596 View MSA. No confident structure predictions are available.
    2 View Details [113..180] deduced N/A Confident ab initio structure predictions are available.
    3 View Details [181..359] PSI-BLAST 25.69897 RNase III endonuclease catalytic domain
    4 View Details [360..471] PSI-BLAST 10.154902 Staufen, domain III

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2
    Term Confidence Notes
  • endoribonuclease activity, producing 5'-phosphomonoesters
    		•  2.96839328209237 bayes_pls_golite062009
  • ribonuclease activity
    		•  2.94599627195218 bayes_pls_golite062009
  • endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  2.83903486346863 bayes_pls_golite062009
  • ribonuclease III activity
    		•  2.48909442352541 bayes_pls_golite062009
  • nuclease activity
    		•  2.39439402087394 bayes_pls_golite062009
  • binding
    		•  2.32833343930107 bayes_pls_golite062009
  • nucleic acid binding
    		•  1.98461935735212 bayes_pls_golite062009
  • endonuclease activity
    		•  1.82613111953108 bayes_pls_golite062009
  • RNA binding
    		•  1.43330249905245 bayes_pls_golite062009
  • catalytic activity
    		•  1.04704963996426 bayes_pls_golite062009
  • endoribonuclease activity
    		•  1.01755329276132 bayes_pls_golite062009
  • hydrolase activity, acting on ester bonds
    		•  0.627113558693086 bayes_pls_golite062009
  • protein binding
    		•  0.625556404096386 bayes_pls_golite062009
    3
    Term Confidence Notes
  • binding
    		•  3.81869789149138 bayes_pls_golite062009
  • nucleic acid binding
    		•  3.63840462420908 bayes_pls_golite062009
  • RNA binding
    		•  3.49736268261512 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.36373437225982 bayes_pls_golite062009
  • DNA binding
    		•  2.27199216614247 bayes_pls_golite062009
  • protein binding
    		•  1.64057905923545 bayes_pls_golite062009
  • double-stranded RNA binding
    		•  1.46317494664076 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  1.43500771925528 bayes_pls_golite062009
  • structural molecule activity
    		•  1.28116258970047 bayes_pls_golite062009
  • transcription factor activity
    		•  1.06321736079473 bayes_pls_golite062009
  • transcription activator activity
    		•  0.434769929118334 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.403469167264307 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.184664228687648 bayes_pls_golite062009
    4 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle