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Protein Overview: ths-PA

General Information:
Name(s) found: ths-PA / FBpp0087137 [FlyBase]
Description(s) found:
Found 19 descriptions.
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  • The gene thisbe is referred to in FlyBase by the symbol Dmel\ths (CG12443, FBgn0033652). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 2R:7677874..7699520. It has the cytological map location 48C3-48C4. It is reported to have molecular function</span>: fibroblast growth factor receptor binding. There is experimental evidence that it is involved in the biological process</span>: glial cell differentiation; hindgut morphogenesis; heart development; larval somatic muscle development; mesoderm development. 10 alleles are reported. The phenotypes of these alleles are annotated with: glial cell; abdominal ventral oblique muscle 4; abdominal ventral oblique muscle 6; mesoderm; segment border muscle; ventral oblique muscle; eye photoreceptor cell; abdominal ventral oblique muscle 5. It has one annotated transcript and one annotated polypeptide. [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 748 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: heart development [IMP]
    larval somatic muscle development [IMP]
    mesoderm development [IGI][IMP]
    fibroblast growth factor receptor signaling pathway [TAS]
    hindgut morphogenesis [IMP]
    glial cell differentiation [IMP]
    Molecular Function: growth factor activity [IEA]
    fibroblast growth factor receptor binding [NAS][TAS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSNQLERLLF FIVVISGALC TVEDYVIMSQ CAHNKAIHIA AEGTVSVTDT SQIQNITIVG  60
   61 FPDYLNNEFK IALYAKETRR YLCFNDNWRL VGMRELRDTC YFNETIVHGY FVFRSVVDLQ 120
  121 RRVGFTHRGK PVGPKKSVND ACYMFNKIEA EQFFRHHHNN GNSGNNNGNG SGNDNGNGSN 180
  181 NSRKPPRNNK NNRHKSNNQN QKLQQQQEHH GHNNNNNNVI LNNSNTSLSS TNKKQLAINR 240
  241 QRQQQQQHQV RHHHNDPSLL LRRQQHEKKQ KRRKQQKQQQ HQQRVSASPT NPMPATPTAA 300
  301 PAATPTVAAT SPATATRSTT AAMSSKRKGR RRKAKVRPKA QQQQQLQLLA TAATSPYTDD 360
  361 TLYGSSSSSS STGFEDLDIY NSSSSSGSSS SLDPWSTWST IDSFSGSSTT ATSDDSISSS 420
  421 SSSNYDAWAT YITEMEAEAS AMTPEMGGND TELMQYEAEL VDDPEAESTA TIETKATSVT 480
  481 STIAATAATT TSTAGSQLVI EQTPLARSNI SNKSSSSTKA TPTATSQTET AQSTQQPSRH 540
  541 RSNSREDHLD NSDMLLAGEN EVKPQQPRKL LWTVQPPLAT RGSTLATLVA TPEQQHTSTT 600
  601 ATAATTPEQH VAPSLFSVDK NINSNLNNTL TEASPTATST SSITSATTMK RPIRKFTKKL 660
  661 MATPYHQLTY VRNAGGDIDI DNLDNISVYP VLYDGDLEGN GGGNSSDGGF SGFLPTSTTS 720
  721 HLTEPIRIGM NRIRPNKTLH WFTHQRFA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..207] FFAS03 5.25 No description for 2p23A was found.
    2 View Details [208..391] deduced N/A No confident structure predictions are available.
    3 View Details [392..498] deduced N/A No confident structure predictions are available.
    4 View Details [499..653] MSA 3.114988 View MSA. No confident structure predictions are available.
    5 View Details [654..748] deduced N/A No confident structure predictions are available.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    [View Details]
    Source: Reynolds et al. 2008. Manuscript submitted Philius confidence legend
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