Protein Overview: orb-PF

General Information:
Name(s) found:	orb-PF / FBpp0290706 [FlyBase]
Description(s) found: SHOW ONLY BEST	gi\|25009796\|gb\|AAN71070.1\| AT14906p [Drosophila melanogaster] [NCBI NR] The gene oo18 RNA-binding protein is referred to in FlyBase by the symbol Dmel\orb (CG10868, FBgn0004882). It is a protein_coding_gene from Drosophila melanogaster. Its sequence location is 3R:19090364..19106571. It has the cytological map location 94E9. There is experimental evidence that it has the molecular function</span>: protein binding. There is experimental evidence that it is involved in the biological process</span>: oocyte anterior/posterior axis specification; regulation of oskar mRNA translation; mRNA polyadenylation; pole plasm oskar mRNA localization; germ cell development; oocyte dorsal/ventral axis specification. 30 alleles are reported. The phenotypes of these alleles are annotated with: germline cyst; chorion; embryonic abdomen; egg; ovary; oocyte; egg chamber; dorsal appendage; synaptonemal complex. It has 6 annotated transcripts and 6 annotated polypeptides. [FlyBase] AT14906p [Drosophila melanogaster] [nrdb_11152004_Chlamydomonas] type=protein; loc=3R:complement(19091575..19091947,19092002..19092387,19092443..19092623,19092684..19093402,19093785..19093979); ID=FBpp0290706; name=orb-PF; parent=FBgn0004882,FBtr0301491; dbxref=FlyBase:FBpp0290706,FlyBase_Annotation_IDs:CG10868-PF; MD5=897274125871669fb418ee8d95166727; length=617; release=r5.21; species=Dmel; [Other_drosophila_na_09-09-2009_reversed.fasta] AT14906p OS=Drosophila melanogaster GN=orb PE=2 SV=1 [UniProt_drosophila_07-01-2011_reversed.fasta] type=protein; loc=3R:complement(19091575..19091947,19092002..19092387,19092443..19092623,19092684..19093402,19093785..19093979); ID=FBpp0290706; name=orb-PF; parent=FBgn0004882,FBtr0301491; dbxref=REFSEQ:NP_001163699,GB_protein:ACZ94994,FlyBase:FBpp0290706,FlyBase_Annotation_IDs:CG10868-PF,FlyMine:FBpp0290706,modMine:FBpp0290706; MD5=897274125871669fb418ee8d95166727; length=617; release=r5.46; species=Dmel; [fly-062812-sfps-sandra-contam.fasta] type=protein; loc=3R:complement(join(23268063..23268257,23266962..23267680,23266721..23266901,23266280..23266665,23265853..23266225)); ID=FBpp0290706; name=orb-PF; parent=FBgn0004882,FBtr0301491; dbxref=REFSEQ:NP_001163699,GB_protein:ACZ94994,FlyBase:FBpp0290706,FlyBase_Annotation_IDs:CG10868-PF,FlyMine:FBpp0290706,modMine:FBpp0290706; MD5=897274125871669fb418ee8d95166727; length=617; release=r6.02; species=Dmel; [fly-2014-05-contam.fasta] type=protein; loc=3R:complement(join(23268063..23268257,23266962..23267680,23266721..23266901,23266280..23266665,23265853..23266225)); ID=FBpp0290706; name=orb-PF; parent=FBgn0004882,FBtr0301491; dbxref=REFSEQ:NP_001163699,GB_protein:ACZ94994,FlyBase:FBpp0290706,FlyBase_Annotation_IDs:CG10868-PF,FlyMine:FBpp0290706,modMine:FBpp0290706; MD5=897274125871669fb418ee8d95166727; length=617; release=r6.07; species=Dmel; [fly-08202015-contam.fasta] Isoform of Q9VCN7, AT14906p OS=Drosophila melanogaster GN=orb PE=2 SV=1 [DROME.fasta.20160308] FBpp0290706 type=protein; loc=3R:complement(join(23268063..23268257,23266962..23267680,23266721..23266901,23266280..23266665,23265853..23266225)); ID=FBpp0290706; name=orb-PF; parent=FBgn0004882,FBtr0301491; dbxref=REFSEQ:NP_001163699,GB_protein:ACZ94994,FlyBase:FBpp0290706,FlyBase_Annotation_IDs:CG10868-PF,FlyMine:FBpp0290706,modMine:FBpp0290706; MD5=897274125871669fb418ee8d95166727; length=617; release=r6.09; species=Dmel; [dmel-all-translation-r6.09.fasta] [fly-122215-dmel-6-09-contam.fasta] type=protein; loc=3R:complement(join(23268063..23268257,23266962..23267680,23266721..23266901,23266280..23266665,23265853..23266225)); ID=FBpp0290706; name=orb-PF; parent=FBgn0004882,FBtr0301491; dbxref=REFSEQ:NP_001163699,GB_protein:ACZ94994,FlyBase:FBpp0290706,FlyBase_Annotation_IDs:CG10868-PF,UniProt/TrEMBL:Q8IHC3,FlyMine:FBpp0290706,modMine:FBpp0290706; MD5=897274125871669fb418ee8d95166727; length=617; release=r6.14; species=Dmel; [fly-dmel-jan2017-sandracontam.fasta]
Organism:	Drosophila melanogaster
Length:	617 amino acids
Gene Ontology:
Cellular Component:	cytoplasm [IDA]
Biological Process:	germ cell development [IMP][TAS] positive regulation of translation [TAS] intracellular mRNA localization [TAS] germarium-derived oocyte fate determination [TAS] oocyte dorsal/ventral axis specification [IMP][TAS] embryonic axis specification [TAS] pole plasm assembly [NAS] mRNA polyadenylation [IMP][ISS] oocyte anterior/posterior axis specification [IMP][TAS] oocyte axis specification [TAS] oogenesis [TAS] regulation of oskar mRNA translation [IMP][TAS] pole plasm oskar mRNA localization [IMP][NAS][TAS] germ-line cyst formation [TAS] positive regulation of oskar mRNA translation [NAS]
Molecular Function:	nucleotide binding [IEA] protein binding [IPI] uridine-rich cytoplasmic polyadenylylation element binding [ISS] mRNA binding [ISS][TAS]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDSINMFYNQ QQQQQQPEQQ GYTSLGNSMG SGLGLSLANA STRSNSPESQ NSSNSTTEQN  60
   61 LLDMINLLSV NSNKIPHQQQ QQQQQQQQQQ QQQQQNQQQL QVQQQHQLQQ QFVNLNRNYE 120
  121 QQISANLGSQ QHGFEHNGVG VGASSSGNEN CFSQYNLENI TSVDMELAKL QNLQRINTLK 180
  181 LLHAQAQQMP LINQLLQSYA GNAIGSVGGS NLGNLMSAGG SSLMTEMAGN VGGIITTNDG 240
  241 HLDRVAKFYK SSAALCDATC TWSGHLPPRS HRMLNYSPKV FLGGIPWDIS EQSLIQIFKP 300
  301 FGSIKVEWPG KEQQAAQPKG YVYIIFESDK QVKALLSACV LQVDDSHCGR NYFFKISSRR 360
  361 IKSKDVEVIP WIIADSNFVR SSSQKLDPTK TVFVGALHGK LTAEGLGNIM DDLFDGVLYA 420
  421 GIDTDKYKYP IGSGRVTFSN FRSYMKAVSA AFIEIRTTKF TKKVQVDPYL EDALCSICGV 480
  481 QHGPYYCREL SCFRYFCRSC WQWQHSCDIV KNHKPLTRNS KSQSLVGIGP SSSNVSLPFS 540
  541 GQRSIRDNRM GNGQHQQHQQ HQYQQQKHRQ LQEYSQPHSL NVMGNSGAAN AAATSMVTLQ 600
  601 QRQIHKVRIQ RQQHQAI

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.75

Protein Overview: orb-PF

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: