Protein Overview: PDE4D_RAT

General Information:
Name(s) found:	PDE4D_RAT [Swiss-Prot]
Description(s) found: SHOW ONLY BEST	gi\|57015263\|sp\|P14270.4\|PDE4D_RAT RecName: Full=cAMP-specific 3',5'-cyclic phosphodiesterase 4D; AltName: Full=DPDE3 [NCBI NR] gi\|2625100\|gb\|AAB95266.1\| cAMP-specific phosphodiesterase [Rattus norvegicus] [NCBI NR] cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Rattus norvegicus GN=Pde4d PE=1 SV=4 [Swiss-Prot] cAMP-specific phosphodiesterase [Rattus norvegicus] [nrdb_11152004_Chlamydomonas] Tax_Id=10116 Splice Isoform 5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D [EBI-IPI_rat_3.17_05-10-2006_con_reversed.fasta] cAMP-specific 3',5'-cyclic phosphodiesterase 4D (DPDE3) [NCBI-RefSeq_multi-organisms_na_08-12-2008_con_reversed.fasta] Tax_Id=10116 CAMP-SPECIFIC PHOSPHODIESTERASE [Xentr4_EBI-IPI_human_mouse_rat_Xenopus_tropicalis_laevis_con_reversed.fasta] Tax_Id=10116 Gene_Symbol=Pde4d Isoform 5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D [rat-ipi-250309-contam.fasta] Isoform 5 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Rattus norvegicus GN=Pde4d [011711_HMR.fasta] Isoform 4 of cAMP-specific 3',5'-cyclic phosphodiesterase 4D OS=Rattus norvegicus GN=Pde4d [120808_122_R_norvegicus.fasta]
Organism:	Rattus norvegicus
Length:	803 amino acids
Gene Ontology:
Cellular Component:	cytoskeleton [IEA] microtubule organizing center [IEA] cytoplasm [IEA] cytosol [UNKNOWN] cell fraction [IDA] plasma membrane [IDA]
Biological Process:	smooth muscle contraction [UNKNOWN] signal transduction [IEA] regulation of protein kinase A signaling cascade [IMP] cAMP catabolic process [UNKNOWN][IDA][IMP] regulation of G-protein coupled receptor protein signaling pathway [IDA] memory [IEP]
Molecular Function:	protein domain specific binding [IPI] metal ion binding [IEA] cAMP binding [IMP] SH3 domain binding [IPI] cyclic-nucleotide phosphodiesterase activity [IDA] 3',5'-cyclic-AMP phosphodiesterase activity [UNKNOWN][IDA][IMP] hydrolase activity [IEA]

Sequence:

Sequence:
[PDR BLAST]
[ProtParam]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MEAEGSSVPA RAGSHEGSDS SGGAALKAPK HLWRHEQHHQ YPLRQPQFRL LHPHHHLPPP  60
   61 PPPSPQPQLQ PPPPPPLPPP PPPPGATRGR YASSGASRVR HRGYSDTERY LYCRAMDRTS 120
  121 YAVETGHRPG LKKSRMSWPS SFQGLRRFDV DNGTSAGRSP LDPMTSPGSG LILQANFVHS 180
  181 QRRESFLYRS DSDYDLSPKS MSRNSSIASD IHGDDLIVTP FAQVLASLRT VRNNFAALTN 240
  241 LQDRAPSKRS PMCNQPSINK ATITEEAYQK LASETLEELD WCLDQLETLQ TRHSVSEMAS 300
  301 NKFKRMLNRE LTHLSEMSRS GNQVSEYISN TFLDKQHEVE IPSPTQKEKE KKKRPMSQIS 360
  361 GVKKLMHSSS LTNSCIPRFG VKTEQEDVLA KELEDVNKWG LHVFRIAELS GNRPLTVIMH 420
  421 TIFQERDLLK TFKIPVDTLI TYLMTLEDHY HADVAYHNNI HAADVVQSTH VLLSTPALEA 480
  481 VFTDLEILAA IFASAIHDVD HPGVSNQFLI NTNSELALMY NDSSVLENHH LAVGFKLLQE 540
  541 ENCDIFQNLT KKQRQSLRKM AIDIVLATDM SKHMNLLADL KTMVETKKVT SSGVLLLDNY 600
  601 SDRIQVLQNM VHCADLSNPT KPLQLYRQWT DRIMEEFFRQ GDRERERGME ISPMCDKHNA 660
  661 SVEKSQVGFI DYIVHPLWET WADLVHPDAQ DILDTLEDNR EWYQSTIPQS PSPAPDDQED 720
  721 GRQGQTEKFQ FELTLEEDGE SDTEKDSGSQ VEEDTSCSDS KTLCTQDSES TEIPLDEQVE 780
  781 EEAVAEEESQ PQTGVADDCC PDT

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

SHOWING SINGLE HITS. [ Hide Single Hits ]

[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Protein predicted to be:	GLOBULAR (No transmembrane regions or signal peptide)
Confidence of classification:	0.99

Protein Overview: PDE4D_RAT

Protein Complex Data

Mass Spectrometry Data

Yeast Two-Hybrid Data

Microscopy / Localization Data

Protein Structure Data

Philius Transmembrane Prediction: