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Protein Overview: EHD2_ARATH

General Information:
Name(s) found: EHD2_ARATH [Swiss-Prot]
Description(s) found:
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  • gi|42566321|ref|NP_567299.2| ATEHD2 (EPS15 HOMOLOGY DOMAIN 2); GTP binding / GTPase/ calcium ion binding [Arabidopsis thaliana] [NCBI NR]
  • gi|190576487|gb|ACE79044.1| At4g05520 [Arabidopsis thaliana] [NCBI NR]
  • EH domain-containing protein 2 OS=Arabidopsis thaliana GN=EHD2 PE=1 SV=1 [Swiss-Prot]
  • calcium-binding EF hand family protein [Arabidopsis thaliana] [nrdb_11152004_Chlamydomonas]
  • Tax_Id=3702 Calcium-binding EF hand family protein [EBI-IPI_Arabidopsis_3.11_12-06-2005_reversed.fasta]
  • | Symbols: | calcium-binding EF hand family protein | chr4:2804519-2807830 FORWARD [TAIR_Arabidopsis_na_04-12-2008_con_reversed.fasta]
  • calcium ion binding [Arabidopsis thaliana] [nr-271106-contam.fasta]
  • | Symbols: ATEHD2, EHD2 | EPS15 homology domain 2 | chr4:2804522-2807833 FORWARD LENGTH=546 [TAIR_A_Thaliana_10_12-14-2010_reversed.fasta]
  • At4g05520 OS=Arabidopsis thaliana GN=EHD2 PE=2 SV=1 [ARATH-contam.fasta]
    • Organism: Arabidopsis thaliana
    Length: 546 amino acids

    Gene Ontology:
    Cellular Component: cytoplasm [IDA]
    membrane [IDA]
    microsome [IDA]
    plasma membrane [IDA]
    Biological Process: endocytosis [IMP]
    Molecular Function: GTP binding [IEA]
    GTPase activity [IEA]
    calcium ion binding [IEA][ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 METSSTISIG SCLKEHQKIY KEWFNIADSD GDGRVSGNDA TKFFAMSKLS RQELKQVWAV  60
   61 ADSKRQGFLG LSEFITAMKL VSLAQEGHEI TSDLLKGSID MKSVELPVLE GLENVVSKQK 120
  121 VSKTNVDVED NVVTKPQVTA KTPWFKSKSI IKPQVNVVTI VDGLKRLYTE KLKPLEVTYR 180
  181 FNDFASPVLT SSDFDAKPMV MLLGQYSTGK TTFIKHLLGC DYPGAHIGPE PTTDRFVVAM 240
  241 SGPDERTIPG NTMAVQADMP FNGLTSFGGA FLSKFECSQM PHPVLDQITL VDTPGVLSGE 300
  301 KQRMQRSYDF TGVISWFASK CDMILLLFDP HKLDISDEFK RVITSLRGNE DKIRVVLNKA 360
  361 DQVDTQQLMR VYGALMWSLG KVLNTPEVVR VYIGSFNDKP INEVAVGPIG KELFEKEQND 420
  421 LLADLMDVPK KACDRKINEF VKRARSAKIN AYIMSHLKKE MPAMMGKSKA QQRLMDNLEE 480
  481 EFGKVQREFH LPAGDFPSVE HFREVLGGYN IDKFEKLKPK MIQAVDDMLG YDIPDLLKKF 540
  541 RNPYDN

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    SHOWING SINGLE HITS. [ Hide Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..140] PSI-BLAST 18.30103 Trapped intermediate of calmodulin
    2 View Details [141..546] PSI-BLAST 71.522879 No description for 2qptA was found.

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • calcium ion binding
    		•  2.10993417016231 bayes_pls_golite062009
  • binding
    		•  1.38572474078647 bayes_pls_golite062009
  • cation binding
    		•  1.32146266431825 bayes_pls_golite062009
  • metal ion binding
    		•  1.32146266431825 bayes_pls_golite062009
  • ion binding
    		•  1.31242124126239 bayes_pls_golite062009
  • ion transmembrane transporter activity
    		•  0.539550637107889 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
    		•  0.49944935937406 bayes_pls_golite062009
  • cation transmembrane transporter activity
    		•  0.486374653947972 bayes_pls_golite062009
  • protein binding
    		•  0.124994709840647 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
    		•  0.0724768101463518 bayes_pls_golite062009
    2 No functions predicted.


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle