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Protein Overview: MCM4_ARATH

General Information:
Name(s) found: MCM4_ARATH [Swiss-Prot]
Description(s) found:
Found 10 descriptions.
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  • DNA replication licensing factor MCM4 OS=Arabidopsis thaliana GN=MCM4 PE=1 SV=1 [Swiss-Prot]
    • Organism: Arabidopsis thaliana
    Length: 847 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: DNA replication initiation [ISS]
    DNA unwinding involved in replication [TAS]
    Molecular Function: nucleotide binding [IEA]
    ATP binding [IEA][ISS]
    DNA binding [IEA][ISS]
    DNA-dependent ATPase activity [ISS]
    nucleoside-triphosphatase activity [IEA]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDSSLGNT NDGPPSPGEN VSSPIENTYS SPAALHRRRR GRSSTPTQFA TPPPPPSRLA  60
   61 SSNSTPPTSR PSAARSKGRN GHGGGGGGGG GGDPGTPMST DEPLPSSDDG EEDGGDDTTP 120
  121 TFVWGTNISV QDVKSAIEMF VKHFREAREN SDDLFREGKY MVSIRKVIEI EGEWIDVDAF 180
  181 DVFDYDPDLY NKMVRYPLEV LAIFDIVLMD IVSTINRLFE KHVQVRIFNL RTSTSMRNLN 240
  241 PSDIEKMISL KGMIIRSSSI IPEIREAVFR CLVCGYFSDP IIVDRGKISE PPTCLKQECM 300
  301 TKNSMTLVHN RCRFADKQIV RLQETPDEIP EGGTPHTVSL LLHDKLVDNG KPGDRIEVTG 360
  361 IYRAMTVRVG PAHRTVKSVF KTYIDCLHIK KASKLRMSAE DPMDVDNSLR RVDEDVELDE 420
  421 EKLRKFQELS KQPDIYERLS RSLAPNIWEL DDVKKGLLCQ LFGGNALNLA SGANFRGDIN 480
  481 ILLVGDPGTS KSQLLQYIHK LSPRGIYTSG RGSSAVGLTA YVAKDPETGE TVLESGALVL 540
  541 SDRGICCIDE FDKMSDSARS MLHEVMEQQT VSIAKAGIIA SLNARTSVLA CANPSGSRYN 600
  601 PRLSVIENIH LPPTLLSRFD LIYLILDKPD EQTDRRLAKH IVALHFENAE SAQEEAIDIT 660
  661 TLTTYVSYAR KNIHPKLSDE AAEELTRGYV ELRKAGKFAG SSKKVITATP RQIESLIRLS 720
  721 EALARMRFSE WVEKHDVDEA FRLLRVAMQQ SATDHATGTI DMDLINTGVS ASERMRRDTF 780
  781 ASSIRDIALE KMQIGGSSMR LSELLEELKK HGGNINTEIH LHDVRKAVAT LASEGFLVAE 840
  841 GDRIKRV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


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    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..125] MSA 3.117997 View MSA. No confident structure predictions are available.
    2 View Details [126..375] PSI-BLAST 53.045757 No description for 2vl6A was found.
    3 View Details [376..462] deduced N/A No confident structure predictions are available.
    4 View Details [463..847] PSI-BLAST 50.0 Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle