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View Structure Prediction Details

Protein: MCM4_ARATH
Organism: Arabidopsis thaliana
Length: 847 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

No multiple sequence alignment data found for MCM4_ARATH.

Predicted Domain #1
Region A:
Residues: [1-125]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MASDSSLGNT NDGPPSPGEN VSSPIENTYS SPAALHRRRR GRSSTPTQFA TPPPPPSRLA  60
   61 SSNSTPPTSR PSAARSKGRN GHGGGGGGGG GGDPGTPMST DEPLPSSDDG EEDGGDDTTP 120
  121 TFVWG

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #2
Region A:
Residues: [126-375]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 TNISVQDVKS AIEMFVKHFR EARENSDDLF REGKYMVSIR KVIEIEGEWI DVDAFDVFDY  60
   61 DPDLYNKMVR YPLEVLAIFD IVLMDIVSTI NRLFEKHVQV RIFNLRTSTS MRNLNPSDIE 120
  121 KMISLKGMII RSSSIIPEIR EAVFRCLVCG YFSDPIIVDR GKISEPPTCL KQECMTKNSM 180
  181 TLVHNRCRFA DKQIVRLQET PDEIPEGGTP HTVSLLLHDK LVDNGKPGDR IEVTGIYRAM 240
  241 TVRVGPAHRT 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 53.045757
Match: 2vl6A
Description: No description for 2vl6A was found.

Predicted Domain #3
Region A:
Residues: [376-462]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 VKSVFKTYID CLHIKKASKL RMSAEDPMDV DNSLRRVDED VELDEEKLRK FQELSKQPDI  60
   61 YERLSRSLAP NIWELDDVKK GLLCQLF

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [463-847]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGNALNLASG ANFRGDINIL LVGDPGTSKS QLLQYIHKLS PRGIYTSGRG SSAVGLTAYV  60
   61 AKDPETGETV LESGALVLSD RGICCIDEFD KMSDSARSML HEVMEQQTVS IAKAGIIASL 120
  121 NARTSVLACA NPSGSRYNPR LSVIENIHLP PTLLSRFDLI YLILDKPDEQ TDRRLAKHIV 180
  181 ALHFENAESA QEEAIDITTL TTYVSYARKN IHPKLSDEAA EELTRGYVEL RKAGKFAGSS 240
  241 KKVITATPRQ IESLIRLSEA LARMRFSEWV EKHDVDEAFR LLRVAMQQSA TDHATGTIDM 300
  301 DLINTGVSAS ERMRRDTFAS SIRDIALEKM QIGGSSMRLS ELLEELKKHG GNINTEIHLH 360
  361 DVRKAVATLA SEGFLVAEGD RIKRV

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 50.0
Match: 1ojlA
Description: Crystal structure of a sigma54-activator suggests the mechanism for the conformational switch necessary for sigma54 binding
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle