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Protein Overview: gi|157830999, gi...

General Information:
Name(s) found: gi|1827675 [NCBI NR]
gi|157830999 [NCBI NR]
gi|119389938 [NCBI NR]
Description(s) found:
Found 7 descriptions.
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  • gi|1827675|pdb|1ERV| Chain , Human Thioredoxin Mutant With Cys 73 Replaced By Ser (Reduced Form) [NCBI NR]
  • gi|157830999|pdb|1ERV|A Chain A, Human Thioredoxin Mutant With Cys 73 Replaced By Ser (Reduced Form) [NCBI NR]
  • gi|119389938|pdb|2HSH|A Chain A, Crystal Structure Of C73s Mutant Of Human Thioredoxin-1 Oxidized With H2o2 [NCBI NR]
    • Organism: Homo sapiens
    Length: 105 amino acids

    Gene Ontology:
    Cellular Component: NONE FOUND
    Biological Process: NONE FOUND
    Molecular Function: NONE FOUND


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD  60
   61 DCQDVASECE VKSMPTFQFF KKGQKVGEFS GANKEKLEAT INELV

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..105] PSI-BLAST 32.522879 HUMAN THIOREDOXIN MUTANT WITH CYS 73 REPLACED BY SER (REDUCED FORM)

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • antioxidant activity
    		•  3.8464796631544 bayes_pls_golite062009
  • peroxidase activity
    		•  3.43831566988273 bayes_pls_golite062009
  • oxidoreductase activity, acting on peroxide as acceptor
    		•  3.43831566988273 bayes_pls_golite062009
  • glutathione peroxidase activity
    		•  2.56524997297011 bayes_pls_golite062009
  • protein disulfide isomerase activity
    		•  2.3913606099687 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, transposing S-S bonds
    		•  2.3913606099687 bayes_pls_golite062009
  • protein-disulfide reductase activity
    		•  2.24066563461479 bayes_pls_golite062009
  • oxidoreductase activity, acting on sulfur group of donors
    		•  2.23310780102446 bayes_pls_golite062009
  • intramolecular oxidoreductase activity, interconverting keto- and enol-groups
    		•  2.18667085747706 bayes_pls_golite062009
  • peroxiredoxin activity
    		•  2.12777217096121 bayes_pls_golite062009
  • selenium binding
    		•  1.97148144306198 bayes_pls_golite062009
  • thioredoxin peroxidase activity
    		•  1.96134566495756 bayes_pls_golite062009
  • disulfide oxidoreductase activity
    		•  1.32811008894503 bayes_pls_golite062009
  • binding
    		•  1.25802922431343 bayes_pls_golite062009
  • transcription regulator activity
    		•  0.96297634785608 bayes_pls_golite062009
  • catalytic activity
    		•  0.672192331361968 bayes_pls_golite062009
  • hydrolase activity
    		•  0.620302638089385 bayes_pls_golite062009
  • protein disulfide oxidoreductase activity
    		•  0.44918717550973 bayes_pls_golite062009
  • glutathione binding
    		•  0.2456976890622 bayes_pls_golite062009
  • transferase activity
    		•  0.245320538630117 bayes_pls_golite062009
  • protein binding
    		•  0.134341907247724 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle