| Protein: | ATXN1 |
| Organism: | Homo sapiens |
| Length: | 815 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ATXN1.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..815] | [1..816] |
|
|
0.0 | [1..815] | [1..809] |
|
|
0.0 | [1..815] | [1..789] |
|
|
0.0 | [1..815] | [1..791] |
|
|
0.0 | [1..815] | [1..812] |
|
|
0.0 | [1..815] | [1..798] |
|
|
3.0E-78 | [636..815] | [73..252] |
|
Region A: Residues: [1-218] |
1 11 21 31 41 51
| | | | | |
1 MKSNQERSNE CLPPKKREIP ATSRSSEEKA PTLPSDNHRV EGTAWLPGNP GGRGHGGGRH 60
61 GPAGTSVELG LQQGIGLHKA LSTGLDYSPP SAPRSVPVAT TLPAAYATPQ PGTPVSPVQY 120
121 AHLPHTFQFI GSSQYSGTYA SFIPSQLIPP TANPVTSAVA SAAGATTPSQ RSQLEAYSTL 180
181 LANMGSLSQT PGHKAEQQQQ QQQQQQQQHQ HQQQQQQQ
|
| Detection Method: |  |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [219-274] |
1 11 21 31 41 51
| | | | | |
1 QQQQQQQHLS RAPGLITPGS PPPAQQNQYV HISSSPQNTG RTASPPAIPV HLHPHQ
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [275-429] |
1 11 21 31 41 51
| | | | | |
1 TMIPHTLTLG PPSQVVMQYA DSGSHFVPRE ATKKAESSRL QQAIQAKEVL NGEMEKSRRY 60
61 GAPSSADLGL GKAGGKSVPH PYESRHVVVH PSPSDYSSRD PSGVRASVMV LPNSNTPAAD 120
121 LEVQQATHRE ASPSTLNDKS GLHLGKPGHR SYALS
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [430-567] |
1 11 21 31 41 51
| | | | | |
1 PHTVIQTTHS ASEPLPVGLP ATAFYAGTQP PVIGYLSGQQ QAITYAGSLP QHLVIPGTQP 60
61 LLIPVGSTDM EASGAAPAIV TSSPQFAAVP HTFVTTALPK SENFNPEALV TQAAYPAMVQ 120
121 AQIHLPVVQS VASPAAAP
|
| Detection Method: | |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [568-693] |
1 11 21 31 41 51
| | | | | |
1 PTLPPYFMKG SIIQLANGEL KKVEDLKTED FIQSAEISND LKIDSSTVER IEDSHSPGVA 60
61 VIQFAVGEHR AQVSVEVLVE YPFFVFGQGW SSCCPERTSQ LFDLPCSKLS VGDVCISLTL 120
121 KNLKNG
|
| Detection Method: | |
| Confidence: | 67.0 |
| Match: | 1oa8A |
| Description: | AXH domain of human spinocerebellar ataxin-1 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| poly(G) RNA binding | 9.63713595128054 | bayes_pls_golite062009 |
| transcription repressor activity | 3.87938017809999 | bayes_pls_golite062009 |
| transcription regulator activity | 3.44900037030135 | bayes_pls_golite062009 |
| nucleic acid binding | 3.11421838242937 | bayes_pls_golite062009 |
| RNA binding | 2.52330994423305 | bayes_pls_golite062009 |
| binding | 2.24516466558786 | bayes_pls_golite062009 |
| poly-pyrimidine tract binding | 2.14262126704047 | bayes_pls_golite062009 |
| protein binding | 1.94841008133032 | bayes_pls_golite062009 |
| single-stranded RNA binding | 1.45078449963459 | bayes_pls_golite062009 |
| poly-purine tract binding | 1.22216556549636 | bayes_pls_golite062009 |
| protein self-association | 1.12839499794765 | bayes_pls_golite062009 |
| poly(U) RNA binding | 0.844689081318551 | bayes_pls_golite062009 |
| identical protein binding | 0.651473260854041 | bayes_pls_golite062009 |
| protein C-terminus binding | 0.163823997825061 | bayes_pls_golite062009 |
|
Region A: Residues: [694-815] |
1 11 21 31 41 51
| | | | | |
1 SVKKGQPVDP ASVLLKHSKA DGLAGSRHRY AEQENGINQG SAQMLSENGE LKFPEKMGLP 60
61 AAPFLTKIEP SKPAATRKRR WSAPESRKLE KSEDEPPLTL PKPSLIPQEV KICIEGRSNV 120
121 GK
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
