YRC Public Data Repository - Protein Structure Prediction

Protein:	HINT1_MOUSE
Organism:	Mus musculus
Length:	126 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HINT1_MOUSE.

Description	E-value	Query Range	Subject Range
gi\|109490737 - gi\|109490737\|ref\|XP_001074494.1\| PREDICTED: similar to Histidine triad nucleotide-binding protein 1 ...	183.0	[0..1]	[126..68]
gi\|7658009 - gi\|7658009\|dbj\|BAA94873.1\| protein kinase C inhibitor [Anas platyrhynchos] gi\|7658005 - gi\|7658005\|dbj\|BAA94871.1\| protein kinase C inhibitor [Coturnix japonica]	181.0	[0..1]	[126..1]
gi\|7415601, gi\|7... - gi\|7415603\|dbj\|BAA93455.1\| protein kinase C inhibitor [Gallus gallus], gi\|7415601\|dbj\|BAA93454.1\| pr...	180.0	[0..1]	[126..1]
gi\|493051, gi\|28... - gi\|493051\|gb\|AAA18396.1\| putative protein kinase C inhibitor, gi\|28461243\|ref\|NP_787006.1\| histidine...	179.0	[0..1]	[126..1]
gi\|73971081 - gi\|73971081\|ref\|XP_531895.2\| PREDICTED: similar to histidine triad nucleotide binding protein 1 [Can...	179.0	[0..1]	[126..1]
HINT1_RABIT - Histidine triad nucleotide-binding protein 1 OS=Oryctolagus cuniculus GN=HINT1 PE=1 SV=2	178.0	[0..1]	[126..1]
gi\|47218227 - gi\|47218227\|emb\|CAF97091.1\| unnamed protein product [Tetraodon nigroviridis]	177.0	[0..1]	[126..1]
gi\|51873772, gi\|... - gi\|51873772\|gb\|AAH78475.1\| MGC85233 protein [Xenopus laevis], gi\|147907158\|ref\|NP_001087193.1\| MGC85...	177.0	[0..1]	[126..1]

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Predicted Domain #1

Region A:
Residues: [1-126]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MADEIAKAQV AQPGGDTIFG KIIRKEIPAK IIFEDDRCLA FHDISPQAPT HFLVIPKKHI  60
   61 SQISVADDDD ESLLGHLMIV GKKCAADLGL KRGYRMVVNE GADGGQSVYH IHLHVLGGRQ 120
  121 MNWPPG

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	45.522879
Match:	1rzyA
Description:	Crystal structure of rabbit Hint complexed with N-ethylsulfamoyladenosine
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
binding	1.71599870633602	bayes_pls_golite062009
pyrophosphatase activity	1.08634513422834	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	1.06844766073798	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	1.06801208560744	bayes_pls_golite062009
nucleoside-triphosphatase activity	0.5306871213471	bayes_pls_golite062009
nucleic acid binding	0.415463551462796	bayes_pls_golite062009
protein binding	0.315946879872005	bayes_pls_golite062009
hydrolase activity	0.196597931631016	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: