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View Structure Prediction Details

Protein: Psi-PA
Organism: Drosophila melanogaster
Length: 716 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for Psi-PA.

Description E-value Query
Range
Subject
Range
IF2B2_PONAB - Insulin-like growth factor 2 mRNA-binding protein 2 OS=Pongo abelii GN=IGF2BP2 PE=2 SV=1
IF2B2_PONPY - Insulin-like growth factor 2 mRNA-binding protein 2 - Pongo pygmaeus (Orangutan)
290.0 [0..9] [432..161]

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Predicted Domain #1
Region A:
Residues: [1-120]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSSGSGGGGG GGGGPGGASI TQAIAQAAAV AARLAASAGT SCEEQIRLPE SVAGAFMGRS  60
   61 SNDTITHIQA ESGVKVQVMQ DQDRVIMLRG QRDTVTKGRE MIQNMANRAG GGQVEVLLTI 120
  121 

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 13.30103
Match: 1e3hA
Description: Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
Matching Structure (courtesy of the PDB):

Predicted Domain #2
Region A:
Residues: [121-321]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 NMPPPGPSGY PPYQEIMIPG AKVGLVIGKG GDTIKQLQEK TGAKMIIIQD GPNQELIKPL  60
   61 RISGEAQKIE HAKQMVLDLI AQKDAQGQQQ GGRGGGGGGG GPGMGFNNFN NGNGGESTEV 120
  121 FVPKIAVGVV IGKGGDMIRK IQTECGCKLQ FIQGKNDEMG DRRCVIQGTR QQVDDAKRTI 180
  181 DGLIENVMQR NGMNRNGNGG G

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 28.0
Match: 2annA
Description: No description for 2annA was found.

Predicted Domain #3
Region A:
Residues: [322-424]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 GGPGGDSGNS NYGYGYGVNH AQGGREEITF LVPASKCGIV IGRGGETIKL INQQSGAHTE  60
   61 MDRNASNPPN EKLFKSKGTT DQVEAARQMI SEKINMELNV ISR

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 20.522879
Match: 1j4wA
Description: Far upstream binding element, FBP, KH3 and KH4 domains
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
binding 0.766407798661875 bayes_pls_golite062009
nucleic acid binding 0.1608635436815 bayes_pls_golite062009
RNA binding 0.0205643208063799 bayes_pls_golite062009

Predicted Domain #4
Region A:
Residues: [425-607]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KPIGGGPGGG GGNSGGGQNN SHHNQQQGGY GGQNQMQGGD PNSGAGYQQQ PWGGPYGQQG  60
   61 WDPSGQQQQM AMANQGGSAA GGASGGQDYS AQWIEYYKQM GCHREAEMIE QQMKAKQAGG 120
  121 SSGPVQQQQP QQQQQSQQQT GGAGAGGADY SAQWAEYYRS VGKIEEAEAI EKTLKNKQNG 180
  181 SGG

[Run NCBI BLAST on this sequence.]

Detection Method: deduced

Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [608-716]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 QSSTPNPSQG GSGQQQPNPA AAAAAAAAAA AAAGGYGQSM TPTQYAQYSQ YYAAAAAAGG  60
   61 QPQGAPQPGG GQSGGPPGNY PGNYPGAGYG GYPGAPGQQQ QKSHKNDNH

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 6.522879
Match: 1m2vB
Description: Sec24
Matching Structure (courtesy of the PDB):

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle